CAS 1852-50-2|Estriol 16α-(β-D-glucuronide)

Introduction:Basic information about CAS 1852-50-2|Estriol 16α-(β-D-glucuronide), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameEstriol 16α-(β-D-glucuronide)
CAS Number1852-50-2Molecular Weight464.50500
Density1.51g/cm3Boiling Point738.3ºC at 760mmHg
Molecular FormulaC24H32O9Melting Point/
MSDSChineseUSAFlash Point253.5ºC
Symbol
GHS08
Signal WordWarning

Names

NameEstriol-16beta-D-glucopyranosiduronic acid
SynonymMore Synonyms

Estriol 16α-(β-D-glucuronide) BiologicalActivity

DescriptionEstriol 16α-(β-D-glucuronide) is an endogenous metabolite present in Urine that can be used for the research of Pregnancy[1][2].
Related CatalogResearch Areas >>Others
In VitroEndogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
References

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.  

[2]. Yang YJ, et al. Direct determination of estriol 3- and 16-glucuronides in pregnancy urine by column-switching liquid chromatography with electrospray tandem mass spectrometry. Biomed Chromatogr. 2003 Jun;17(4):219-25.  

Chemical & Physical Properties

Density1.51g/cm3
Boiling Point738.3ºC at 760mmHg
Molecular FormulaC24H32O9
Molecular Weight464.50500
Flash Point253.5ºC
Exact Mass464.20500
PSA156.91000
LogP0.49650
Vapour Pressure6.95E-23mmHg at 25°C
Index of Refraction1.667
InChIKeyFQYGGFDZJFIDPU-JRSYHJKYSA-N
SMILESCC12CCC3c4ccc(O)cc4CCC3C1CC(OC1OC(C(=O)O)C(O)C(O)C1O)C2O
Storage condition-20°C

Safety Information

Symbol
GHS08
Signal WordWarning
Hazard StatementsH351
Precautionary StatementsP281
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXn: Harmful;
Risk Phrases40
Safety Phrases36/37
RIDADRNONH for all modes of transport
WGK Germany3

Articles31

More Articles
Radioimmunoassay of 2-hydroxyestrone.

Steroids 31(2) , 249-58, (1978)

Under the protection of ascorbic acid a 2-hydroxyestrone bovine serum albumin conjugate was prepared containing intact 2-hydroxyestrone as determined by gas chromatographymass spectometry. Using this ...

The dynamic changes of several reproductive hormones during termination of early pregnancy by RU486 in combination with PG-05 in Chinese women.

Adv. Contracept. 4(4) , 319-26, (1988)

8 pregnant women (below 49 days of amenorrhea) were administered 600 mg RU486 orally in a single dosage, and 1 mg PG-05 as a vaginal suppository 48 h afterwards. The plasma beta-hCG, progesterone, 17 ...

Associations between urinary phthalate monoesters and thyroid hormones in pregnant women.

Hum. Reprod. 22(10) , 2715-22, (2007)

Maternal hypothyroidism during pregnancy can cause adverse effects in the fetus. Scientific evidence has shown that probable thyroid-like function of some phthalates in vitro and in vivo, and phthalat...

Synonyms

estriol 16 glucuronide
Estriol O16-glucuronide
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