Introduction：Basic information about CAS 107756-30-9|A 61603, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | A 61603 |
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| CAS Number | 107756-30-9 | Molecular Weight | 309.38400 |
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| Density | / | Boiling Point | 548.4ºC at 760mmHg |
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| Molecular Formula | C14H19N3O3S | Melting Point | / |
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| MSDS | / | Flash Point | 285.5ºC |
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Names
| Name | N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide,hydrobromide |
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A 61603 BiologicalActivity
| Description | A-61603 is a selective α1A-adrenergic receptor agonist[1]. A-61603 increases the frequency of spontaneous Ca2+ transients in rat ventricular myocytes in vitro[2]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>GPCR/G Protein >>Adrenergic Receptor |
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| Target | α1A-adrenergic receptor |
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| References | [1]. Meyer MD, et al. Synthesis and in vitro characterization of N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8- tetrahydronaphthalen-1-yl]methanesulfonamide and its enantiomers: A novel selective α1A receptor agonist. J. Med. Chem. 39(20), 4116-4119 (1996). |
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Chemical & Physical Properties
| Boiling Point | 548.4ºC at 760mmHg |
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| Molecular Formula | C14H19N3O3S |
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| Molecular Weight | 309.38400 |
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| Flash Point | 285.5ºC |
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| Exact Mass | 309.11500 |
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| PSA | 99.17000 |
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| LogP | 2.10350 |
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| Vapour Pressure | 1.23E-12mmHg at 25°C |
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| InChIKey | LRFLWCZMTGTUEP-UHFFFAOYSA-N |
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| SMILES | Br.CS(=O)(=O)Nc1c(O)ccc2c1CCCC2C1=NCCN1 |
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