Introduction：Basic information about CAS 34915-68-9|Bunitrolol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bunitrolol |
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| CAS Number | 34915-68-9 | Molecular Weight | 248.32 |
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| Density | 1.09g/cm3 | Boiling Point | 414.2ºC at 760mmHg |
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| Molecular Formula | C14H20N2O2 | Melting Point | / |
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| MSDS | / | Flash Point | 204.3ºC |
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Names
| Name | 2-[3-(tert-butylamino)-2-hydroxypropoxy]benzonitrile |
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| Synonym | More Synonyms |
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Bunitrolol BiologicalActivity
| Description | Bunitrolol is a beta-adrenergic antagonist. Bunitrolol has intrinsic sympathomimetic activity. Bunitrolol can be used for the research of ischemic myocardium[1]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>GPCR/G Protein >>Adrenergic Receptor |
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| References | [1]. Chiba K, et al. Effects of bunitrolol on ischemic myocardial energy metabolism in dogs. J Pharm Sci. 1993 Apr;82(4):384-8. |
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Chemical & Physical Properties
| Density | 1.09g/cm3 |
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| Boiling Point | 414.2ºC at 760mmHg |
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| Molecular Formula | C14H20N2O2 |
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| Molecular Weight | 248.32 |
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| Flash Point | 204.3ºC |
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| Exact Mass | 248.15200 |
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| PSA | 65.28000 |
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| LogP | 2.07698 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DI2530000
- CHEMICAL NAME :
- Benzonitrile, o-(3-(tert-butylamino)-2-hydroxypropoxy)-
- CAS REGISTRY NUMBER :
- 34915-68-9
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C14-H20-N2-O2
- MOLECULAR WEIGHT :
- 248.36
- WISWESSER LINE NOTATION :
- NCR BO1YQ1MX1&1&1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 46 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year: 17,341,1972
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Safety Information
Customs
| HS Code | 2926909090 |
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| Summary | HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| Bunitrolol |
| Stresson |
| Bunitrolol HCl |
| 2-Nitrilo-N-tert-butylphenoxypropanolamine |
| KO-1366 |
