Introduction：Basic information about CAS 37308-75-1|Flavokawain C, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Flavokawain C |
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| CAS Number | 37308-75-1 | Molecular Weight | 300.306 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 556.0±50.0 °C at 760 mmHg |
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| Molecular Formula | C17H16O5 | Melting Point | 179-182℃ |
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| MSDS | / | Flash Point | 207.3±23.6 °C |
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Names
| Name | (E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one |
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| Synonym | More Synonyms |
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Flavokawain C BiologicalActivity
| Description | Flavokawain C is a natural chalcone found in Kava root. Flavokawain C exerts cytotoxicity against human cancer cell lines, with an IC50 of 12.75 μM for HCT 116 cells[1]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer |
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| References | [1]. Phang CW, et al. Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells. PLoS One. 2016 Feb 9;11(2):e0148775. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 556.0±50.0 °C at 760 mmHg |
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| Melting Point | 179-182℃ |
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| Molecular Formula | C17H16O5 |
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| Molecular Weight | 300.306 |
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| Flash Point | 207.3±23.6 °C |
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| Exact Mass | 300.099762 |
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| PSA | 75.99000 |
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| LogP | 3.48 |
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| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
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| Index of Refraction | 1.637 |
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| InChIKey | UXUFMIJZNYXWDX-VMPITWQZSA-N |
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| SMILES | COc1cc(O)c(C(=O)C=Cc2ccc(O)cc2)c(OC)c1 |
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Synonyms
| 4',6'-dimethoxy-2',4-dihydroxychalcone |
| Flavokavain C |
| 1-(2-hydroxy-4,6-dimethoxy)phenyl-3-(4-hydroxy)phenyl-2-propen-1-one |
| 2',4-Dihydroxy-4',6'-dimethoxychalcone |
| 2'-hydroxy-4,6'-dimethoxychalcone |
| 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-, (2E)- |
| (E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one |
| 2299311 |
| (2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one |
| Flavokawain C |
| Flavokawin C |
| flavokawin |
| (2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one |
| QR D1U1VR BQ DO1 FO1 &&E Form |
| 4',6'-di-O-methylchalconaringenin |
