Introduction：Basic information about CAS 34221-41-5|Echinatin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Echinatin |
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| CAS Number | 34221-41-5 | Molecular Weight | 270.280 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 509.8±50.0 °C at 760 mmHg |
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| Molecular Formula | C16H14O4 | Melting Point | 210ºC (dec.) |
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| MSDS | / | Flash Point | 193.3±23.6 °C |
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Names
| Name | (E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one |
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| Synonym | More Synonyms |
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Echinatin BiologicalActivity
| Description | Echinatin is a chalcone isolated from the Chinese herbal medicine Gancao with hepatoprotective and anti-inflammatory effects. Echinatin may undergo an electron transfer (ET) and a proton transfer (PT) to cause the antioxidant action in aqueous solution[1]. Echinatin can be quickly absorbed and eliminated and extensively distributed with an absolute bioavailability of approximately 6.81% in Rat[2]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Liang M, et al. Antioxidant Mechanisms of Echinatin and Licochalcone A. Molecules. 2018 Dec 20;24(1). [2]. Inoue B, et al. The effects of echinatin and its related compounds on the mitochondrial energy transfer reaction. J Toxicol Sci. 1982 Nov;7(4):245-54. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 509.8±50.0 °C at 760 mmHg |
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| Melting Point | 210ºC (dec.) |
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| Molecular Formula | C16H14O4 |
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| Molecular Weight | 270.280 |
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| Flash Point | 193.3±23.6 °C |
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| Exact Mass | 270.089203 |
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| PSA | 66.76000 |
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| LogP | 3.23 |
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| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
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| Index of Refraction | 1.658 |
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| InChIKey | QJKMIJNRNRLQSS-WEVVVXLNSA-N |
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| SMILES | COc1cc(O)ccc1C=CC(=O)c1ccc(O)cc1 |
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| Storage condition | 2-8°C |
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Safety Information
Customs
| HS Code | 2914509090 |
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| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
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Synonyms
| Echinatin |
| Retrochalcone |
| (2E)-3-(4-Hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one |
| Echinantin |
| 2-Propen-1-one, 3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)- |
| 2-methoxy-4,4'-dihydroxychalcone |
| (2E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one |
| loureirin C |
| (E)-4,4'-Dihydroxy-2-methoxychalcone |
| 4',4-dihydroxy-2-methoxychalcone |
