CAS 4753-04-2|Uridine,2'-chloro-2'-deoxy-

Introduction:Basic information about CAS 4753-04-2|Uridine,2'-chloro-2'-deoxy-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameUridine,2'-chloro-2'-deoxy-
CAS Number4753-04-2Molecular Weight262.65
Density1.67g/cm3Boiling Point/
Molecular FormulaC9H11ClN2O5Melting Point/
MSDS/Flash Point/

Names

Name2'-chloro-2'-deoxyuridine
SynonymMore Synonyms

Uridine,2'-chloro-2'-deoxy- BiologicalActivity

Description2′-Chloro-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

Density1.67g/cm3
Molecular FormulaC9H11ClN2O5
Molecular Weight262.65
Exact Mass262.03600
PSA104.55000
Index of Refraction1.643
InChIKeyXOTUXDQKWDTKSI-XVFCMESISA-N
SMILESO=c1ccn(C2OC(CO)C(O)C2Cl)c(=O)[nH]1
Storage condition-20°C

Safety Information

Hazard CodesXn

Synonyms

2-CHLORO-2-DEOXYURIDINE
MFCD00057379
2'-Chlor-2'-deoxy-uridin
2'-chloro-dU
2'-Chlor-2'-desoxyuridin
2'-Chloro-2'-deoxy-uridin
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