Introduction:Basic information about CAS 4753-04-2|Uridine,2'-chloro-2'-deoxy-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Uridine,2'-chloro-2'-deoxy- |
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| CAS Number | 4753-04-2 | Molecular Weight | 262.65 |
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| Density | 1.67g/cm3 | Boiling Point | / |
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| Molecular Formula | C9H11ClN2O5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2'-chloro-2'-deoxyuridine |
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| Synonym | More Synonyms |
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Uridine,2'-chloro-2'-deoxy- BiologicalActivity
| Description | 2′-Chloro-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.67g/cm3 |
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| Molecular Formula | C9H11ClN2O5 |
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| Molecular Weight | 262.65 |
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| Exact Mass | 262.03600 |
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| PSA | 104.55000 |
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| Index of Refraction | 1.643 |
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| InChIKey | XOTUXDQKWDTKSI-XVFCMESISA-N |
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| SMILES | O=c1ccn(C2OC(CO)C(O)C2Cl)c(=O)[nH]1 |
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| Storage condition | -20°C |
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Safety Information
Synonyms
| 2-CHLORO-2-DEOXYURIDINE |
| MFCD00057379 |
| 2'-Chlor-2'-deoxy-uridin |
| 2'-chloro-dU |
| 2'-Chlor-2'-desoxyuridin |
| 2'-Chloro-2'-deoxy-uridin |