CAS 3351-86-8|Fucoxanthin

Introduction：Basic information about CAS 3351-86-8|Fucoxanthin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Fucoxanthin BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Articles49
7. Synonyms

Common Name	Fucoxanthin
CAS Number	3351-86-8	Molecular Weight	676.922
Density	1.1±0.1 g/cm3	Boiling Point	786.5±60.0 °C at 760 mmHg
Molecular Formula	C₄₂H₅₈O₆	Melting Point	166-168ºC
MSDS	ChineseUSA	Flash Point	228.5±26.4 °C
Symbol	GHS02, GHS07	Signal Word	Danger

Names

Name	fucoxanthin
Synonym	More Synonyms

Fucoxanthin BiologicalActivity

Description	Fucoxanthin is a marine carotenoid and shows anti-obesity, anti-diabetic, anti-oxidant, anti-inflammatory and anticancer activities.
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>CancerResearch Areas >>Inflammation/ImmunologyResearch Areas >>Metabolic Disease
References	[1]. Gammone MA, et al. Anti-obesity activity of the marine carotenoid fucoxanthin. Mar Drugs. 2015 Apr 13;13(4):2196-214.

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	786.5±60.0 °C at 760 mmHg
Melting Point	166-168ºC
Molecular Formula	C₄₂H₅₈O₆
Molecular Weight	676.922
Flash Point	228.5±26.4 °C
Exact Mass	676.433899
PSA	96.36000
LogP	7.70
Vapour Pressure	0.0±6.2 mmHg at 25°C
Index of Refraction	1.563
InChIKey	SJWWTRQNNRNTPU-ABBNZJFMSA-N
SMILES	CC(=O)OC1CC(C)(C)C(=C=CC(C)=CC=CC(C)=CC=CC=C(C)C=CC=C(C)C(=O)CC23OC2(C)CC(O)CC3(C)C)C(C)(O)C1
Storage condition	?20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FI0329800

CHEMICAL NAME :: beta,beta-Carotene, 3'-(acetyloxy)-6',7'-didehydro-5,6-epoxy-5,5',6,6',7, 8-hexahydro-3,5'- dihydroxy-8-oxo-, (3S,3'S,5R,5'R,6S,6'R)-

CAS REGISTRY NUMBER :: 3351-86-8

BEILSTEIN REFERENCE NO. :: 0073179

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C42-H58-O6

MOLECULAR WEIGHT :: 659.00

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Human Cells - not otherwise specified

DOSE/DURATION :: 5 mg/L

REFERENCE :: CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 55,75,1990

Safety Information

Symbol	GHS02, GHS07
Signal Word	Danger
Hazard Statements	H225-H319
Precautionary Statements	P210-P280-P305 + P351 + P338-P337 + P313-P403 + P235
Hazard Codes	F
Risk Phrases	11
Safety Phrases	7-16
RIDADR	NONH for all modes of transport

Articles49

Fucoxanthin induces apoptosis in human cervical cancer cell line HeLa via PI3K/Akt pathway.

Tumour Biol. 35(11) , 11261-7, (2014)

Cervical cancer (CC) is a malignant neoplasm arising from cells originating in the cervix uteri, among the top causes of death from cancer in women. In a gene expression profiling study of metabolic r...

Biological Properties of Fucoxanthin in Oil Recovered from Two Brown Seaweeds Using Supercritical CO2 Extraction.

Mar. Drugs 13 , 3422-42, (2015)

The bioactive materials in brown seaweeds hold great interest for developing new drugs and healthy foods. The oil content in brown seaweeds (Saccharina japonica and Sargassum horneri) was extracted by...

The anti-apoptotic effect of fucoxanthin on carbon tetrachloride-induced hepatotoxicity.

J. Toxicol. Sci. 38(1) , 115-26, (2013)

This study evaluated the anti-apoptotic activity of fucoxanthin in carbon tetrachloride (CCl(4))-induced hepatotoxicity. An in vitro study using the 3-(4,5-dimethylthiazol-2-yl) 2,5-diphenyltetrazoliu...

Synonyms

[(1S,3R)-3-hydroxy-4-[(3E,5E,7E,9E,11E,13E,15E)-18-[(1R,3S,6S)-3-hydroxy-1,5,5-trimethyl-7-oxabicyclo[4.1.0]heptan-6-yl]-3,7,12,16-tetramethyl-17-oxooctadeca-1,3,5,7,9,11,13,15-octaenylidene]-3,5,5-trimethylcyclohexyl] acetate

β,β-Caroten-8-one, 3'-(acetyloxy)-6',7'-didehydro-5,5',6,6',7,8-hexahydro-3,5,5',6-tetrahydroxy-, (3S,3'S,5R,5'R,6S,6'R,8'R)-

MFCD01745140

(3S,3'S,5R,5'R,6S,6'R,8'R)-3,5,5',6-Tetrahydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-β,β-caroten-3'-yl acetate

Fucoxanthin

Fucoxanthin DISCONTINUED

(3S,3'S,5R,5'R,6S,6'R)-3'-(Acetyloxy)-6',7'-didehydro-5,6-epoxy-5,5',6,6',7,8-hexahydro-3,5'-dihydroxy-8-oxo-b,b-carotene

(3S,3'S,5R,5'R,6S,6'R)-3'-(acetyloxy)-6',7'-didehydro-5,6-epoxy-5,5',6,6',7,8-hexahydro-3,5'-dihydroxy-8-oxo-β,β-carotene

all-trans-Fucoxanthin

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