CAS 463-40-1|Linolenic acid
Introduction：Basic information about CAS 463-40-1|Linolenic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Linolenic acid | ||
|---|---|---|---|
| CAS Number | 463-40-1 | Molecular Weight | 278.430 |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 443.4±0.0 °C at 760 mmHg |
| Molecular Formula | C18H30O2 | Melting Point | -11 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 275.7±14.4 °C |
Names
| Name | α-linolenic acid |
|---|---|
| Synonym | More Synonyms |
Linolenic acid BiologicalActivity
| Description | α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>PI3K/Akt/mTOR >>PI3KSignaling Pathways >>PI3K/Akt/mTOR >>Akt |
| Target | PI3K Akt |
| In Vitro | α-Linolenic acid converses into the longer chain fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)[1]. |
| In Vivo | α-Linolenic acid (50, 100, 250 mg/kg; for 10 days) can completely inhibit collagen- and adrenaline-induced thrombosis in mice at 250 mg/kg[1]. α-Linolenic acid (35, 70, 175 mg/kg) suppresses A-V thrombus formation in rats (weighing at 250 ~ 300 g)[1]. α-Linolenic acid (70 or 175 mg/kg) inhibits collagen stimulated platelet aggregation in rats[1]. Animal Model: Mice weighing at 18 ~ 22 g[1] Dosage: 50, 100, 250 mg/kg Administration: For 10 days Result: Completely inhibited collagen- and adrenaline-induced thrombosis at 250 mg/kg. |
| References | [1]. Yang Q, et al. Anti-thrombotic effects of α-linolenic acid isolated from Zanthoxylum bungeanum Maxim seeds. BMC Complement Altern Med. 2014 Sep 23;14:348. |
Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 443.4±0.0 °C at 760 mmHg |
| Melting Point | -11 °C(lit.) |
| Molecular Formula | C18H30O2 |
| Molecular Weight | 278.430 |
| Flash Point | 275.7±14.4 °C |
| Exact Mass | 278.224579 |
| PSA | 37.30000 |
| LogP | 6.50 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.491 |
| Storage condition | 2-8°C |
| Water Solubility | INSOLUBLE |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves |
|---|---|
| Hazard Codes | F;Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| HS Code | 2916190090 |
Customs
| HS Code | 2916190090 |
|---|---|
| Summary | 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0% |
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Synonyms
| EINECS 207-334-8 |
| (9Z,12Z,15Z)-linolenic acid |
| 9,12,15-all-cis-Octadecatrienoic acid |
| 9,12,15-Octadecatrienoic acid, (9Z,12Z,15Z)- |
| Linolein,2-mono |
| 2-linoleoyl-sn-glycerol |
| 2-Monolinolein |
| (9Z,12Z,15Z)-Octadeca-9,12,15-trienoic acid |
| 2-Glyceryl 9,12-octadecadienoate |
| 9,12-Octadecadienoic acid (Z,Z)-,2-hydroxy-1-(hydroxymethyl)ethyl ester |
| linoleic acid monoacylglycerol |
| 9,12,15-OCTADECATRIENOIC ACID, (Z,Z,Z)- |
| Glyceryl 2-linoleate |
| 9Z,12Z,15Z-octadecatrienic acid |
| 2-monolinoleoylglycerol |
| 9Z,12Z,15Z-Octadecatrienoic acid |
| (9Z,12Z,15Z)-9,12,15-Octadecatrienoic acid |
| MFCD00065720 |
| a-Linolenic Acid |
| octadecatrienoic acid |
| 9,12,15-octadecatrienoic acid |
| alpha-linolenic acid |
| (all-Z)-9,12,15-Octadecatrienoic acid |
| (9Z,12Z)-1,3-dihydroxypropan-2-yl octadeca-9,12-dienoate |
| Linolenic acid |
| C18:3 (9,12,15-cis all) |
| 2-Linoleoylglycerol |
| 9,12,15-Octadecatrienoic acid, (9Z,12Z,15Z)- (9CI) |
