CAS 47141-42-4|LEVOBUNOLOL

Introduction：Basic information about CAS 47141-42-4|LEVOBUNOLOL, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. LEVOBUNOLOL BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	LEVOBUNOLOL
CAS Number	47141-42-4	Molecular Weight	291.38500
Density	/	Boiling Point	/
Molecular Formula	C₁₇H₂₅NO₃	Melting Point	205 - 210ºC
MSDS	/	Flash Point	/

Names

Name	levobunolol
Synonym	More Synonyms

LEVOBUNOLOL BiologicalActivity

Description	Levobunolol (l-Bunolol) is a potent and nonselective β-adrenergic receptor antagonist. Levobunolol is an ocular hypotensive agent and lowers mean intraocular pressure (IOP). Levobunolol can be used for glaucoma and superior oblique myokymia (SOM) research[1][2][3].
Related Catalog	Research Areas >>OthersSignaling Pathways >>GPCR/G Protein >>Adrenergic Receptor
Target	β-adrenoceptor
References	[1]. Mohammadi M, et al. Injectable drug depot engineered to release multiple ophthalmic therapeutic agents with precise time profiles for postoperative treatment following ocular surgery. Acta Biomater. 2018 Jun;73:90-102. [2]. Kumar, N, et al. Extended levobunolol release from Eudragit nanoparticle-laden contact lenses for glaucoma therapy. Futur J Pharm Sci 6, 109 (2020). [3]. Zhang M, et al. Superior oblique myokymia treated with levobunolol. J AAPOS. 2018 Feb;22(1):67-69.e2.

Chemical & Physical Properties

Melting Point	205 - 210ºC
Molecular Formula	C₁₇H₂₅NO₃
Molecular Weight	291.38500
Exact Mass	291.18300
PSA	58.56000
LogP	2.72430
InChIKey	IXHBTMCLRNMKHZ-LBPRGKRZSA-N
SMILES	CC(C)(C)NCC(O)COc1cccc2c1CCCC2=O
Storage condition	-20?C Freezer, Under Inert Atmosphere

Safety Information

HS Code	2922509090

Customs

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

LEVOBUNOLOL

Betagan

Levobunololum

MFCD00864586

Akbeta

5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-2H-naphthalen-1-one

UNII-G6317AOI7K

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