Introduction：Basic information about CAS 65896-16-4|Romifidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Romifidine |
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| CAS Number | 65896-16-4 | Molecular Weight | 258.090 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 303.2±52.0 °C at 760 mmHg |
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| Molecular Formula | C9H9BrFN3 | Melting Point | 110 °C |
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| MSDS | / | Flash Point | 137.2±30.7 °C |
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Names
| Name | N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine |
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| Synonym | More Synonyms |
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Romifidine BiologicalActivity
| Description | Romifidine is an α2 adrenergic receptor agonist. Romifidine shows sedation effects in vivo[1][2]. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Neurological Disease |
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| In Vivo | Romifidine (80 μg/kg; i.v. once) produces sedative effects with significantly greater drooping during the 45-90 min time period in welsh mountain ponies[1]. Romifidine (40, 80 and 120 mg/kg; i.v. at seven-day intervals) shows a shallower and shorter-lived sedation than with detomidine in horses[2]. |
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| References | [1]. England GC, et al. A comparison of the sedative effects of three alpha 2-adrenoceptor agonists (romifidine, detomidine and xylazine) in the horse. J Vet Pharmacol Ther. 1992 Jun;15(2):194-201. [2]. Hamm D, et al. Sedative and analgesic effects of detomidine and romifidine in horses. Vet Rec. 1995 Apr 1;136(13):324-7. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 303.2±52.0 °C at 760 mmHg |
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| Melting Point | 110 °C |
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| Molecular Formula | C9H9BrFN3 |
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| Molecular Weight | 258.090 |
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| Flash Point | 137.2±30.7 °C |
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| Exact Mass | 256.996368 |
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| PSA | 36.42000 |
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| LogP | 1.02 |
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| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
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| Index of Refraction | 1.662 |
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| InChIKey | KDPNLRQZHDJRFU-UHFFFAOYSA-N |
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| SMILES | Fc1cccc(Br)c1NC1=NCCN1 |
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Safety Information
Customs
| HS Code | 2933290090 |
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| Summary | 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Romifidina [Spanish] |
| 2-(6-bromo-2-fluorophenylimino)-imidazolidine |
| Romifidinum [Latin] |
| 2-bromo-6-fluoro-N-(2-imidazolidinylidene)-benzamine |
| 2-[(2-bromo-6-fluorophenyl)-imino]-imidazolidine |
| N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine |
| 2-[(2-Brom-6-fluorphenyl)imino]imidazolidin |
| Romifidina |
| Romifidinum |
| N-(2-bromo-6-fluoro-phenyl)-4,5-dihydro-1H-imidazol-2-amine |
| (2-bromo-6-fluoro-phenyl)-(4,5-dihydro-1H-imidazol-2-yl)-amine |
| 1H-Imidazol-2-amine, N-(2-bromo-6-fluorophenyl)-4,5-dihydro- |
| Romifidine |
| Sedivet |
