CAS 6004-24-6|Cetylpyridinium chloride monohydrate

Introduction：Basic information about CAS 6004-24-6|Cetylpyridinium chloride monohydrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Cetylpyridinium chloride monohydrate BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Articles57
8. Synonyms

Common Name	Cetylpyridinium chloride monohydrate
CAS Number	6004-24-6	Molecular Weight	358.001
Density	/	Boiling Point	/
Molecular Formula	C₂₁H₄₀ClNO	Melting Point	81-84 °C
MSDS	ChineseUSA	Flash Point	/
Symbol	GHS06, GHS09	Signal Word	Danger

Names

Name	cetylpyridinium chloride monohydrate
Synonym	More Synonyms

Cetylpyridinium chloride monohydrate BiologicalActivity

Description	Cetylpyridinium chloride monohydrate is a cationic quaternary ammonium compound, used in some types of mouthwashes, toothpastes, throat and nasal sprays, is an antiseptic that kills bacteria and other microorganisms, effective in preventing dental plaque and reducing gingivitis.
Related Catalog	Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection

Chemical & Physical Properties

Melting Point	81-84 °C
Molecular Formula	C₂₁H₄₀ClNO
Molecular Weight	358.001
Exact Mass	357.279846
PSA	13.11000
LogP	3.39510
InChIKey	NFCRBQADEGXVDL-UHFFFAOYSA-M
SMILES	CCCCCCCCCCCCCCCC[n+]1ccccc1.O.[Cl-]
Stability	Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid anhydrides, acid chlorides.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU5075000

CHEMICAL NAME :: Pyridinium, 1-hexadecyl-, chloride, monohydrate

CAS REGISTRY NUMBER :: 6004-24-6

LAST UPDATED :: 199603

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C21-H38-N.Cl.H2-O

MOLECULAR WEIGHT :: 358.07

WISWESSER LINE NOTATION :: T6KJ A16 &G &QH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

Safety Information

Symbol	GHS06, GHS09
Signal Word	Danger
Hazard Statements	H301-H315-H319-H330-H335-H410
Precautionary Statements	P260-P304 + P340 + P310-P305 + P351 + P338-P403 + P233
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T+:Verytoxic;
Risk Phrases	R25;R26;R38
Safety Phrases	S28-S36/37-S45-S7/9-S61-S26
RIDADR	UN 2811 6.1/PG 1
WGK Germany	3
RTECS	UU5075000
Packaging Group	I
Hazard Class	6.1
HS Code	2933399090

Customs

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles57

Exosomes: novel effectors of human platelet lysate activity.

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Despite the popularity of platelet-rich plasma (PRP) and platelet lysate (PL) in orthopaedic practice, the mechanism of action and the effectiveness of these therapeutic tools are still controversial....

Impact of lipid dynamic behavior on physical stability, in vitro release and skin permeation of genistein-loaded lipid nanoparticles.

Eur. J. Pharm. Biopharm. 88(1) , 40-7, (2014)

The aim of this study was to develop lipid nanoparticles to deliver genistein (GEN) to deeper skin layers. To do so, the impact of lipid dynamic behavior (nanoparticle flexibility) on stability, relea...

Effect of silver nanoparticles on human mesenchymal stem cell differentiation.

Beilstein J. Nanotechnol. 5 , 2058-69, (2014)

Silver nanoparticles (Ag-NP) are one of the fastest growing products in nano-medicine due to their enhanced antibacterial activity at the nanoscale level. In biomedicine, hundreds of products have bee...

Synonyms

Cetylpyridinum chloride

Cetylpyridinium chloride monohydrate

CETYLPYRIDINII CHLORIDUM

MFCD00149977

CPC MONOHYDRATE

EINECS 204-593-9

Pyridinium, 1-hexadecyl-, chloride, hydrate (1:1:1)

cetylpyridinium chloride

Chlorohexadecyl pyridine

Ceetylpyridiniumchloride

1-Hexadecylpyridin-1-ium chloride hydrate

Cetylpyridinium chloride hydrate

hexadecylpyridium chloride

cetyl pyridium chloride

1-Hexadecylpyridinium chloride hydrate (1:1:1)

Halset

N-CETYLPYRIDINIUM CHLORIDE MONOHYDRATE

Hexadecylpyridinium Chloride Monohydrate

Dobendan

Sprol

1-cetylpyridin-1-ium chloride hydrate

CPC

1-hexadecylpyridinium chloride monohydrate

N-hexadecylpyridinium chloride monohydrate

CPC hydrate

CETYL PYRIDIMUM CHLORIDE

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