CAS 496-15-1|Indoline

Introduction：Basic information about CAS 496-15-1|Indoline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles30
7. Synonyms

Common Name	Indoline
CAS Number	496-15-1	Molecular Weight	119.164
Density	1.0±0.1 g/cm3	Boiling Point	227.2±10.0 °C at 760 mmHg
Molecular Formula	C₈H₉N	Melting Point	-21 °C
MSDS	ChineseUSA	Flash Point	92.8±0.0 °C

Names

Name	indoline
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	227.2±10.0 °C at 760 mmHg
Melting Point	-21 °C
Molecular Formula	C₈H₉N
Molecular Weight	119.164
Flash Point	92.8±0.0 °C
Exact Mass	119.073502
PSA	12.03000
LogP	1.63
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.562
InChIKey	LPAGFVYQRIESJQ-UHFFFAOYSA-N
SMILES	c1ccc2c(c1)CCN2
Storage condition	2-8°C
Water Solubility	5 g/L (20 ºC)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL6906300

CHEMICAL NAME :: 1H-Indole, 2,3-dihydro-

CAS REGISTRY NUMBER :: 496-15-1

BEILSTEIN REFERENCE NO. :: 0111915

LAST UPDATED :: 199710

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C8-H9-N

MOLECULAR WEIGHT :: 119.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >238 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 94,1620,1974

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S23-S24/25-S37/39-S26
WGK Germany	3
RTECS	NL6906300
HS Code	2933990090

Customs

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles30

Palladium-catalyzed insertion of N-tosylhydrazones for the synthesis of isoindolines.

Chem. Commun. (Camb.) 49(31) , 3254-6, (2013)

Isoindolines are synthesized by palladium-catalyzed coupling reaction of N-(2-iodobenzyl) anilines with α,β-unsaturated N-tosylhydrazones. The reaction has several potential advantages: (1) toleration...

FeCl3-mediated Friedel-Crafts hydroarylation with electrophilic N-acetyl indoles for the synthesis of benzofuroindolines.

Angew. Chem. Int. Ed. Engl. 51(50) , 12546-50, (2012)

IRONic electrophilic indoles! The C3-regioselective hydroarylation of N-acetyl indoles with aromatic nucleophiles mediated by FeCl(3) features a rare example of the electrophilic reactivity of the ind...

Identification and Testing of Novel CARP-1 Functional Mimetic Compounds as Inhibitors of Non-Small Cell Lung and Triple Negative Breast Cancers.

J. Biomed. Nanotechnol. 11 , 1608-27, (2015)

The triple negative breast cancer (TNBCs) and non-small cell lung cancers (NSCLCs) often acquire mutations that contribute to failure of drugs in clinic and poor prognosis, thus presenting an urgent n...

Synonyms

2,3-dihydro-1H-1-indole

Indoline

IDN

trans-dihydroindole

2,3-dihydro-1H-indole

EINECS 207-816-8

MFCD00005705

2,3-DIHYDROINDOLE

1H-Indole, 2,3-dihydro-

1-Azaindan

2,3-Dihydro-1H-indol

dihydroindole

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