CAS 452-80-2|2-fluoro-4-methyl-aniline
Introduction：Basic information about CAS 452-80-2|2-fluoro-4-methyl-aniline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-fluoro-4-methyl-aniline | ||
|---|---|---|---|
| CAS Number | 452-80-2 | Molecular Weight | 125.144 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 196.5±0.0 °C at 760 mmHg |
| Molecular Formula | C7H8FN | Melting Point | 3 °C |
| MSDS | ChineseUSA | Flash Point | 79.4±0.0 °C |
| Symbol | GHS06 | Signal Word | Danger |
Names
| Name | 2-Fluoro-4-Methylaniline |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 196.5±0.0 °C at 760 mmHg |
| Melting Point | 3 °C |
| Molecular Formula | C7H8FN |
| Molecular Weight | 125.144 |
| Flash Point | 79.4±0.0 °C |
| Exact Mass | 125.064079 |
| PSA | 26.02000 |
| LogP | 1.73 |
| Vapour Pressure | 0.4±0.3 mmHg at 25°C |
| Index of Refraction | 1.542 |
| InChIKey | ZQEXBVHABAJPHJ-UHFFFAOYSA-N |
| SMILES | Cc1ccc(N)c(F)c1 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - wild bird species
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972
Safety Information
| Symbol | GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H311-H315-H319-H331-H335 |
| Precautionary Statements | P261-P280-P301 + P310-P305 + P351 + P338-P311 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | T:Toxic; |
| Risk Phrases | R23/24/25;R36/37/38 |
| Safety Phrases | S26-S36/37/39-S45 |
| RIDADR | UN 2810 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | XU6650000 |
| Packaging Group | III |
| Hazard Class | 6.1 |
| HS Code | 2921430090 |
Customs
| HS Code | 2921430090 |
|---|---|
| Summary | HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Articles3
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| Rat liver microsomal metabolism of 2-halogenated 4-methylanilines. Xenobiotica 22(12) , 1403-23, (1992) 1. Rat liver microsomal metabolism of 2-fluoro-, 2-chloro- and 2-bromo-4-methylaniline was investigated using h.p.l.c. Metabolites identified include products from side-chain C-hydroxylation (benzyl a... | |
| Indoline derivatives as 5-HT(2C) receptor agonists. Bioorg. Med. Chem. Lett. 14 , 2367-2370, (2004) A series of 1-(1-indolinyl)-2-propylamines was synthesised and evaluated as 5-HT(2C) receptor agonists for the treatment of obesity. The general methods of synthesis of the precursor indoles are descr... |
Synonyms
| 4-Amino-3-fluorotoluene |
| Benzenamine, 2-fluoro-4-methyl- |
| p-Toluidine, 2-fluoro- |
| 2-Fluoro-4-methylaniline |
| Aniline, 2-fluoro-4-methyl- |
| 2-Fluoro-4-methyaniline |
| ZR BF D1 |
| MFCD00040975 |
| EINECS 259-564-3 |
| 2-Fluoro-4-methylbenzenamine |
| 2-Fluoro-p-toluidine |
| 2-fluoro-4-methyl-aniline |
