CAS 189064-06-0|Acetyl-Amyloid β-Protein (15-20) amide trifluoroacetate salt
Introduction：Basic information about CAS 189064-06-0|Acetyl-Amyloid β-Protein (15-20) amide trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Acetly-β Amyloid (15-20), Amide is a peptides fragment. Acetly-β Amyloid (15-20), Amide inhibits the β-sheet formation and stabilizes structure of Aβ (1–40) peptide. Acetly-β Amyloid (15-20), Amide can be used in study Alzheimer’s disease[1].
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Research Areas >>Neurological Disease
References
[1]. Lin SY, et al. Fourier transform infrared spectroscopy used to evidence the prevention of beta-sheet formation of amyloid beta(1-40) peptide by a short amyloid fragment. Int J Biol Macromol. 2003 Sep;32(3-5):173-7.
Arrest of beta-amyloid fibril formation by a pentapeptide ligand.
J. Biol. Chem. 271 , 8545-8548, (1996)
Polymerization of amyloid beta-peptide (Abeta) into amyloid fibrils is a critical step in the pathogenesis of Alzheimer's disease. Here, we show that peptides incorporating a short Abeta fragment (KLV...
Controlling amyloid beta-peptide fibril formation with protease-stable ligands.
J. Biol. Chem. 272 , 12601-12605, (1997)
We have previously shown that short peptides incorporating the sequence KLVFF can bind to the approximately 40amino acid residue Alzheimer amyloid beta-peptide (Abeta) and disrupt amyloid fibril forma...
