CAS 65882-12-4|Ac-Lys(Ac)-D-Ala-D-lactic acid

Introduction:Basic information about CAS 65882-12-4|Ac-Lys(Ac)-D-Ala-D-lactic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameAc-Lys(Ac)-D-Ala-D-lactic acid
CAS Number65882-12-4Molecular Weight373.401
Density1.2±0.1 g/cm3Boiling Point740.5±60.0 °C at 760 mmHg
Molecular FormulaC16H27N3O7Melting Point/
MSDS/Flash Point401.7±32.9 °C

Names

Name2-[2-(2,6-diacetamidohexanoylamino)propanoyloxy]propanoic acid
SynonymMore Synonyms

Ac-Lys(Ac)-D-Ala-D-lactic acid BiologicalActivity

DescriptionAc-Lys(Ac)-D-Ala-D-Lactic acid is a depsipeptide substrate for penicillin-sensitive D-alanine carboxypeptidases (DD-carboxypeptidases)[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Rasmussen JR, et al. Utilization of a depsipeptide substrate for trapping acyl-enzyme intermediates of penicillin-sensitive D-alanine carboxypeptidases. Proc Natl Acad Sci U S A. 1978 Jan;75(1):84-8.  

Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point740.5±60.0 °C at 760 mmHg
Molecular FormulaC16H27N3O7
Molecular Weight373.401
Flash Point401.7±32.9 °C
Exact Mass373.184906
PSA150.90000
LogP-1.02
Vapour Pressure0.0±5.3 mmHg at 25°C
Index of Refraction1.495
InChIKeyLOEWINUIHJAOMZ-UHFFFAOYSA-N
SMILESCC(=O)NCCCCC(NC(C)=O)C(=O)NC(C)C(=O)OC(C)C(=O)O

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport
HS Code2924199090

Customs

HS Code2924199090
Summary2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles1

More Articles
Mechanism of penicillin action: penicillin and substrate bind covalently to the same active site serine in two bacterial D-alanine carboxypeptidases.

Proc. Natl. Acad. Sci. U. S. A. 76 , 2730, (1979)

It has been hypothesized that penicillin acts as a structural analog of the acyl-D-alanyl-D-alanine terminus of nascent bacterial cell wall and that it consequently binds to and acylates the active si...

Synonyms

Nalpha,Nepsilon-Diacetyl-Lys-D-Ala-D-lactic acid
N|A,N|A-Diacetyl-Lys-D-Ala-D-lactic acid
(1R)-1-Carboxyethyl N,N-diacetyl-L-lysyl-D-alaninate
D-Alanine, N,N-diacetyl-L-lysyl-, (1R)-1-carboxyethyl ester
AC-LYS(AC)-D-ALA-D-LACTIC ACID
CAS 168781-78-0|Ac-Ile-Tyr-Gly-Glu-Phe-NH2
CAS 28845-97-8|Ac-Lys-D-Ala-D-Ala-OH
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