CAS 775-06-4|DL-m-Tyrosine
| Common Name | DL-m-Tyrosine | ||
|---|---|---|---|
| CAS Number | 775-06-4 | Molecular Weight | 181.189 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 387.2±32.0 °C at 760 mmHg |
| Molecular Formula | C9H11NO3 | Melting Point | 280-285 °C (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | 188.0±25.1 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 3-(3-Hydroxyphenyl)-DL-alanine |
|---|---|
| Synonym | More Synonyms |
DL-m-Tyrosine BiologicalActivity
| Description | DL-m-Tyrosine shows effects on Arabidopsis root growth. Carbidopa combination with DL-m-tyrosine shows a potent hypotensive effect[1][2]. |
|---|---|
| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others |
| References | [1]. Schuster B, et al. The mechanism of action of phenylalanine ammonia-lyase: the role of prosthetic dehydroalanine. Proc Natl Acad Sci U S A. 1995 Aug 29;92(18):8433-7. [2]. Bertin C, et al. Grass roots chemistry: meta-tyrosine, an herbicidal nonprotein amino acid. Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16964-9. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 387.2±32.0 °C at 760 mmHg |
| Melting Point | 280-285 °C (dec.)(lit.) |
| Molecular Formula | C9H11NO3 |
| Molecular Weight | 181.189 |
| Flash Point | 188.0±25.1 °C |
| Exact Mass | 181.073898 |
| PSA | 83.55000 |
| LogP | 0.38 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.614 |
| InChIKey | JZKXXXDKRQWDET-UHFFFAOYSA-N |
| SMILES | NC(Cc1cccc(O)c1)C(=O)O |
| Storage condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02549 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1400 mg/kg
- SEX/DURATION :
- female 1-7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 38,251,1976
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | YP2278000 |
| HS Code | 2922509090 |
Customs
| HS Code | 2922509090 |
|---|---|
| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles28
More Articles| Pleiotropic physiological consequences of feedback-insensitive phenylalanine biosynthesis in Arabidopsis thaliana. Plant J. 63(5) , 823-35, (2010) A large proportion of plant carbon flow passes through the shikimate pathway to phenylalanine, which serves as a precursor for numerous secondary metabolites. To identify new regulatory mechanisms aff... | |
| Concomitant tumor resistance: the role of tyrosine isomers in the mechanisms of metastases control. Cancer Res. 72(5) , 1043-50, (2012) Concomitant tumor resistance (CR) is a phenomenon in which a tumor-bearing host is resistant to the growth of secondary tumor implants and metastasis. Although previous studies indicated that T-cell-d... | |
| Inhibitory effect of a two day fast on reactive oxygen species (ROS) generation by leucocytes and plasma ortho-tyrosine and meta-tyrosine concentrations. J. Clin. Endocrinol. Metab. 86(6) , 2899-902, (2001) ABSTRACT Since glucose intake acutely increases reactive oxygen species (ROS) generation by polymorphonuclear leucocytes (PMN) and mononuclear cells (MNC), we have now investigated whether a fast over... |
Synonyms
| DL-m-Tyrosine;; DL-3-Tyrosine;; 3-(3-Hydroxyphenyl)-DL-alanine |
| DL-M-TYROSINE |
| EINECS 212-270-9 |
| 3-hydroxy-phenylalanine |
| 3-Hydroxy-DL-phenylalanine |
| DL-3-TYROSINE |
| D/L-3-hydroxy-phenylalanine |
| 3-Hydroxyphenylalanine |
| DL-META-TYROSINE |
| D,L-M-TYR |
| M-TYROSINE |
| 3-(m-Hydroxyphenyl)alanine |
| Phenylalanine, 3-hydroxy- |
| 2-amino-3-(3-hydroxyphenyl)propanoic acid |
| UNII:45KGG1D4BI |
| 2-ammonio-3-(3-hydroxyphenyl)propanoate |
| DL-3-OH-Phe |
| MFCD00002597 |
