Introduction:Basic information about CAS 637-21-8|homatropine hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | homatropine hydrochloride |
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| CAS Number | 637-21-8 | Molecular Weight | 311.80 |
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| Density | / | Boiling Point | 403.3ºC at 760 mmHg |
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| Molecular Formula | C16H22ClNO3 | Melting Point | 226ºC |
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| MSDS | / | Flash Point | 197.7ºC |
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Names
| Name | (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenylacetate,hydrochloride |
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| Synonym | More Synonyms |
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homatropine hydrochloride BiologicalActivity
| Description | Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs[1]. |
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| Related Catalog | Signaling Pathways >>Neuronal Signaling >>mAChRResearch Areas >>OthersSignaling Pathways >>GPCR/G Protein >>mAChR |
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| References | [1]. Gore A, et al. Efficacy assessment of various anticholinergic agents against topical sarin-induced miosis and visual impairment in rats. Toxicol Sci. 2012 Apr;126(2):515-24. |
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Chemical & Physical Properties
| Boiling Point | 403.3ºC at 760 mmHg |
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| Melting Point | 226ºC |
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| Molecular Formula | C16H22ClNO3 |
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| Molecular Weight | 311.80 |
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| Flash Point | 197.7ºC |
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| Exact Mass | 311.12900 |
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| PSA | 49.77000 |
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| LogP | 2.62830 |
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| InChIKey | FRMDDIJBLQNNTC-ISXUQMITSA-N |
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| SMILES | CN1C2CCC1CC(OC(=O)C(O)c1ccccc1)C2.Cl |
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Safety Information
| Hazard Codes | Xn |
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| RIDADR | UN 1544 6.1/PG 3 |
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| Packaging Group | III |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| HOMATROPINE HCL |
| AC1Q3EBX |
| DL-Mandelsaeure-tropan-3endo-ylester,Hydrochlorid |
| Homatropine hydrochloride |
| 8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetatehydrochloride(1:1) |
| CTK8B4043 |
| UNII-365MO3S3N9 |
| DL-mandelic acid-tropane-3endo-ylester,hydrochloride |
| 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester,hydrochloride |
| EINECS 211-280-0 |
| MFCD00050613 |
| AC1L2STU |