CAS 645-12-5|5-Nitro-2-furancarboxylic Acid
Introduction：Basic information about CAS 645-12-5|5-Nitro-2-furancarboxylic Acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-Nitro-2-furancarboxylic Acid | ||
|---|---|---|---|
| CAS Number | 645-12-5 | Molecular Weight | 157.08100 |
| Density | 1.72 g/cm3 (-53 C) | Boiling Point | 332ºC |
| Molecular Formula | C5H3NO5 | Melting Point | 185-189 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 5-Nitro-2-furoic acid |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.72 g/cm3 (-53 C) |
|---|---|
| Boiling Point | 332ºC |
| Melting Point | 185-189 °C(lit.) |
| Molecular Formula | C5H3NO5 |
| Molecular Weight | 157.08100 |
| Exact Mass | 157.00100 |
| PSA | 96.26000 |
| LogP | 1.40920 |
| InChIKey | IODMEDPPCXSFLD-UHFFFAOYSA-N |
| SMILES | O=C(O)c1ccc([N+](=O)[O-])o1 |
| Storage condition | -20°C |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- Phage inhibition capacity
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 1 gm/L
- REFERENCE :
- VIRLAX Virology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1955- Volume(issue)/page/year: 99,257,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6649 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)
- TYPE OF TEST :
- Phage inhibition capacity
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 1 gm/L
- REFERENCE :
- VIRLAX Virology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1955- Volume(issue)/page/year: 99,257,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6649 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R36/37/38;R68 |
| Safety Phrases | S37/39-S36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | LV2012000 |
Articles4
More Articles| 5-Nitro-2-furoic acid hydrazones: design, synthesis and in vitro antimycobacterial evaluation against log and starved phase cultures. Bioorg. Med. Chem. Lett. 20 , 4313-6, (2010) Various 5-nitro-2-furoic acid hydrazones were synthesized and evaluated for in vitro activities against log and starved phase culture of two mycobacterial species and Mycobacterium tuberculosis (MTB) ... | |
| Formation of methemoglobin by photoactivation of nitrofurantoin or of 5-nitrofurfural in rats exposed to UV-A light. Toxicology 51(2-3) , 255-66, (1988) The antibacterial drug nitrofurantoin (NFT) is notorious for causing hemolytic anemia, which may be related to the methemoglobinemia, another side-effect of NFT. As NFT is photolabile, and nitrite, we... | |
| Synthesis of some new [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b][1,3,4] thiadiazoles starting from 5-nitro-2-furoic acid and evaluation of their antimicrobial activity. Bioorg. Med. Chem. 19 , 4506-12, (2011) New series of fused 1,2,4-triazoles such as, 6-(aryl)-3-(5-nitrofuran-2-yl)-5,6-dihydro-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles 4-8, 6-(alkyl/aryl amino)-3-(5-nitrofuran-2-yl)-[1,2,4]triazolo[3,4-b]... |
Synonyms
| MFCD00003240 |
| 5-nitrofuran-2-carboxylic acid |
| EINECS 211-432-6 |
