CAS 18390-00-6|PTIO
| Common Name | PTIO | ||
|---|---|---|---|
| CAS Number | 18390-00-6 | Molecular Weight | 233.286 |
| Density | 1.17g/cm3 | Boiling Point | 359.7ºC at 760mmHg |
| Molecular Formula | C13H17N2O2 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 171.3ºC |
Names
| Name | ptio |
|---|---|
| Synonym | More Synonyms |
PTIO BiologicalActivity
| Description | PTIO is a specific scavenger of NO. PTIO reacts with •NO to form the corresponding imino nitroxides and •NO2[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Xia JL , et al. Putrescine regulates nitric oxide accumulation in Ganoderma lucidum partly by influencing cellular glutamine levels under heat stress. Microbiol Res. 2020;239:126521. [2]. Goldstein S, et al. Reactions of PTIO and carboxy-PTIO with *NO, *NO2, and O2-*. J Biol Chem. 2003;278(51):50949-50955. |
Chemical & Physical Properties
| Density | 1.17g/cm3 |
|---|---|
| Boiling Point | 359.7ºC at 760mmHg |
| Molecular Formula | C13H17N2O2 |
| Molecular Weight | 233.286 |
| Flash Point | 171.3ºC |
| Exact Mass | 233.128998 |
| PSA | 31.99000 |
| LogP | 2.05850 |
| InChIKey | DYUUGILMVYJEHY-UHFFFAOYSA-N |
| SMILES | CC1(C)N([O])C(c2ccccc2)=[N+]([O-])C1(C)C |
Safety Information
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
|---|---|
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
Articles40
More Articles| Nitric oxide induces cancer stem cell-like phenotypes in human lung cancer cells. Am. J. Physiol. Cell Physiol. 308(2) , C89-100, (2015) Even though tremendous advances have been made in the treatment of cancers during the past decades, the success rate among patients with cancer is still dismal, largely because of problems associated ... | |
| Interaction of nNOS with PSD-95 negatively controls regenerative repair after stroke. J. Neurosci. 34(40) , 13535-48, (2014) Stroke is a major public health concern. The lack of effective therapies heightens the need for new therapeutic targets. Mammalian brain has the ability to rewire itself to restore lost functionalitie... | |
| Cardiac contractility in Antarctic teleost is modulated by nitrite through xanthine oxidase and cytochrome p-450 nitrite reductase. Nitric Oxide 49 , 1-7, (2015) In mammalian and non-mammalian vertebrates, nitrite anion, the largest pool of intravascular and tissue nitric oxide storage, represents a key player of many biological processes, including cardiac mo... |
Synonyms
| 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide |
| 2-phenyl-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazole-3-oxide-1-oxyl |
| 2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL |
| 1H-Imidazol-1-yloxy, 4,5-dihydro-4,4,5,5-tetramethyl-3-oxido-2-phenyl- |
| 4,5-Dihydro-4,4,5,5-tetramethyl-3-oxido-2-phenyl-1H-Imidazol-1-yloxy |
| 2-phenyl-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazolyl-1-oxy 3-oxide radical |
| 2-phenyl-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazolyl-1-oxyl-3-N-oxide |
| 2-phenyl-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazol-1-oxyl 3-oxide |
| 4,5-DIHYDRO-4,4,5,5-TETRAMETHYL-2-PHENYL-1H-IMIDAZOL-1-YLOXY-1-OXIDE |
| PTIO |
| 2-Phenyl-4,4,5,5-tetramethylimidazoline 3-oxide 1-oxyl |
| 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide |
| 4,4,5,5-tetramethyl-2-phenyl-4,5-dihydro-1H-imidazole-1-oxyl 3-oxide |
| (4,4,5,5-Tetramethyl-3-oxido-2-phenyl-4,5-dihydro-1H-imidazol-1-yl)oxidanyl |
| 2-phenyl-4,4,5,5-tetramethyl-2,5-dihydro-1H-imidazol-1-oxyl 3-N-oxide |
| (2-Phenyl-4,4,5,5-tetraMethyliMidazoline-3-oxide-1-oxyl) |
| 4,4,5,5-tetramethyl-2-phenyl-4,5-dihydro-1H-imidazole-3-oxide-1-oxyl |
