Introduction：Basic information about CAS 24279-91-2|carboquone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | carboquone |
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| CAS Number | 24279-91-2 | Molecular Weight | 321.32800 |
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| Density | 1.1990 (rough estimate) | Boiling Point | 460.09°C (rough estimate) |
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| Molecular Formula | C15H19N3O5 | Melting Point | 202° (dec) |
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| MSDS | / | Flash Point | / |
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Names
| Name | [2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl]-2-methoxyethyl] carbamate |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.1990 (rough estimate) |
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| Boiling Point | 460.09°C (rough estimate) |
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| Melting Point | 202° (dec) |
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| Molecular Formula | C15H19N3O5 |
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| Molecular Weight | 321.32800 |
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| Exact Mass | 321.13200 |
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| PSA | 101.71000 |
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| Index of Refraction | 1.5600 (estimate) |
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| InChIKey | SHHKQEUPHAENFK-UHFFFAOYSA-N |
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| SMILES | COC(COC(N)=O)C1=C(N2CC2)C(=O)C(C)=C(N2CC2)C1=O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DK3400000
- CHEMICAL NAME :
- p-Benzoquinone, 2,5-bis(1-aziridinyl)-3-(2-hydroxy-1-methoxyethyl)-6- methyl-, carbamate
- CAS REGISTRY NUMBER :
- 24279-91-2
- BEILSTEIN REFERENCE NO. :
- 1400765
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 19
- MOLECULAR FORMULA :
- C15-H19-N3-O5
- MOLECULAR WEIGHT :
- 321.37
- WISWESSER LINE NOTATION :
- T3NTJ A- BL6V DVJ C1 FYO1&1OVZ E- AT3NTJ
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 27300 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3070 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3990 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3620 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 28600 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3440 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Skin and Appendages - hair Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4900 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5430 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 35 mg/kg/5W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Endocrine - changes in spleen weight Related to Chronic Data - changes in testicular weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 42 mg/kg/6W-C
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight Endocrine - changes in thymus weight Related to Chronic Data - changes in testicular weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7 mg/kg/5W-C
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight Endocrine - changes in thymus weight Related to Chronic Data - changes in uterine weight
- TYPE OF TEST :
- DNA damage
MUTATION DATA - TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 10 ug/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 44,3270,1984
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Synonyms
| Esquinon |
| Carbaziloquinone |
| Carbazilequinone |
| 2,5-bis-aziridin-1-yl-3-(2-carbamoyloxy-1-methoxy-ethyl)-6-methyl-[1,4]benzoquinone |
| carboquone |
| Carboquonum [INN-Latin] |
| Carboquona [INN-Spanish] |
| Carbazilquinone |
| Carboquone [INN:JAN] |
| 2,5-bis(1-aziridinyl)-3-(2-carbamoyloxy-1-methoxyethyl)-6-methyl-1,4-benzoquinone |
