CAS 4999-79-5|17-Beta-Estradiol-3-O-Sulfate Sodium
| Common Name | 17-Beta-Estradiol-3-O-Sulfate Sodium | ||
|---|---|---|---|
| CAS Number | 4999-79-5 | Molecular Weight | 374.427 |
| Density | / | Boiling Point | / |
| Molecular Formula | C18H23NaO5S | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS07, GHS08 | Signal Word | Warning |
Names
| Name | 1,3,5[10]-estratriene-3,17beta-diol 3-sulfate sodium salt |
|---|---|
| Synonym | More Synonyms |
17-Beta-Estradiol-3-O-Sulfate Sodium BiologicalActivity
| Description | 17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid[1][2]. |
|---|---|
| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>GABA ReceptorResearch Areas >>Neurological DiseaseSignaling Pathways >>Neuronal Signaling >>GABA Receptor |
| In Vitro | 17β-Estradiol sulfate (sodium) is a neuroactive steroid[1][2]. |
| References | [1]. Li W, et al. Neuroactive steroids and human recombinant rho1 GABAC receptors. J Pharmacol Exp Ther. 2007;323(1):236-247. [2]. Schneider C, et al. A novel enzyme-linked immunosorbent assay for ethynylestradiol using a long-chain biotinylated EE2 derivative. Steroids. 2004;69(4):245-253. |
Chemical & Physical Properties
| Molecular Formula | C18H23NaO5S |
|---|---|
| Molecular Weight | 374.427 |
| Exact Mass | 374.116394 |
| PSA | 95.04000 |
| LogP | 3.82340 |
| InChIKey | LMJQCTISQYSLPF-CMZLOHJFSA-M |
| SMILES | CC12CCC3c4ccc(OS(=O)(=O)[O-])cc4CCC3C1CCC2O.[Na+] |
Safety Information
| Symbol | GHS07, GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H332-H351 |
| Precautionary Statements | P281 |
| Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R20/21/22 |
| Safety Phrases | 22-36 |
| RIDADR | NONH for all modes of transport |
Articles23
More Articles| Sulfotransferase 2A1 forms estradiol-17-sulfate and celecoxib switches the dominant product from estradiol-3-sulfate to estradiol-17-sulfate. J. Steroid Biochem. Mol. Biol. 96(5) , 367-74, (2005) Using recombinant sulfotransferases (SULTs) expressed in E. coli, beta-estradiol (E2) sulfonation was examined to determine which SULT enzyme is responsible for producing E2-17-sulfate (E2-17-S). SULT... | |
| Steroid sulphate secretion by the human ovary in vitro: influence of gonadotrophins, cyclofenil and clomiphene. J. Steroid Biochem. 13(12) , 1401-6, (1980) | |
| [Evidence, in vitro, of estrone and estradiol-17 beta 3-sulfoconjugate hydrolysis in the uterus of pregnant guinea pigs]. C. R. Seances. Acad. Sci. III. 292(9) , 609-12, (1981) The metabolism, in vitro, of [6,7-3H]-oestrone-3-sulfate and [6,7-3H]-oestradiol-17beta-3-sulfate by the uteri of pregnant female Guinea-Pigs has been studied using 900 g supernatants. A hydrolysis of... |
Synonyms
| b-Estradiol 3-sulfate sodium salt |
| Estra-1,3,5(10)-triene-3,17-diol, 3-(hydrogen sulfate), sodium salt, (17β)- (1:1) |
| 17BETA-ESTRADIOL 3-SULFATE SODIUM |
| 17BETA-ESTRADIOL 3-SULFATE SODIUM SALT |
| SODIUM 17B-ESTRADIOL 3-SULFATE |
| oestradiol 3-sulfate,sodium salt |
| 17B-estradiol 3-sulfate sodium |
| 17Beta-Estradiol 3-O-Sulfate Sodium Salt |
| Sodium (17β)-17-hydroxyestra-1,3,5(10)-trien-3-yl sulfate |
