Introduction：Basic information about CAS 646-31-1|Tetracosane, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Tetracosane (ALKANE C24) is a natural product that can be found in Acrostichum aureum. Tetracosane hows cytotoxicity and induces Apoptosis. Tetracosane has the potential for the research of peptic ulcer[1].
Related Catalog
Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Inflammation/Immunology
In Vitro
Tetracosane (0-250 µM; 24, 48 h) 表现出细胞毒性并以时间依赖性方式诱导细胞凋亡[1]。 Cell Cytotoxicity Assay[1] Cell Line: HT-29, MDA-MB-231, AGS cells Concentration: 0-250 µM Incubation Time: Result: Showed cytotoxicity with IC50s of 128.7, >250, >250 µM for HT-29, MDA-MB-231, AGS cells, respectively. Apoptosis Analysis[1] Cell Line: AGS cells Concentration: 500 µg/mL Incubation Time: 24, 48 h Result: Induced apoptosis with the late apoptosis rate of 10% at 24 h and increased to 20% at 48 h.
References
[1]. Uddin SJ, et al. Evaluation of cytotoxic activity of patriscabratine, tetracosane and various flavonoids isolated from the Bangladeshi medicinal plant Acrostichum aureum. Pharm Biol. 2012 Oct;50(10):1276-80.
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