CAS 27430-18-8|4,6(1H,5H)-Pyrimidinedione,5-(2-furanylmethylene)dihydro-2-thioxo-

Introduction：Basic information about CAS 27430-18-8|4,6(1H,5H)-Pyrimidinedione,5-(2-furanylmethylene)dihydro-2-thioxo-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	4,6(1H,5H)-Pyrimidinedione,5-(2-furanylmethylene)dihydro-2-thioxo-
CAS Number	27430-18-8	Molecular Weight	222.22
Density	1.54g/cm3	Boiling Point	/
Molecular Formula	C₉H₆N₂O₃S	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione
Synonym	More Synonyms

BiologicalActivity

Description	CD00509 is a Tdp1 inhibitor, with an IC50 value of 0.71 μM. CD00509 can sensitize breast cancer cells to Camptothecin (HY-16560). CD00509 has anti-tumor activity[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Metabolic Enzyme/Protease >>Phosphodiesterase (PDE)
References	[1]. Laev SS, et al. Tyrosyl-DNA phosphodiesterase inhibitors: Progress and potential. Bioorg Med Chem. 2016 Nov 1;24(21):5017-5027.

Chemical & Physical Properties

Density	1.54g/cm3
Molecular Formula	C₉H₆N₂O₃S
Molecular Weight	222.22
Exact Mass	222.01000
PSA	103.43000
LogP	0.85150
Index of Refraction	1.685
InChIKey	VQRARDATQWRHGF-UHFFFAOYSA-N
SMILES	O=C1NC(=S)NC(=O)C1=Cc1ccco1

Safety Information

HS Code	2934999090

Customs

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

5-(2-furylmethylene)-2-thioxo-1,3-dihydropyrimidine-4,6-dione

5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione

5-furan-2-ylmethylene-2-thioxodihydropyrimidine-4,6-dione

5-furfurylidene-2-thio-barbituric acid

5-Furfuryliden-2-thio-barbitursaeure

5-furfurylidene-2-thioxo-dihydro-pyrimidine-4,6-dione

5-(furan-2'-ylmethylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

Recommended......