Introduction：Basic information about CAS 65673-48-5|m-PEG2-O-Ph-NH2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | m-PEG2-O-Ph-NH2 |
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| CAS Number | 65673-48-5 | Molecular Weight | 211.25800 |
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| Density | 1.086g/cm3 | Boiling Point | 346.2ºC at 760 mmHg |
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| Molecular Formula | C11H17NO3 | Melting Point | / |
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| MSDS | / | Flash Point | 173.9ºC |
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Names
| Name | 4-[2-(2-methoxyethoxy)ethoxy]aniline |
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| Synonym | More Synonyms |
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m-PEG2-O-Ph-NH2 BiologicalActivity
| Description | m-PEG2-O-Ph-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.086g/cm3 |
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| Boiling Point | 346.2ºC at 760 mmHg |
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| Molecular Formula | C11H17NO3 |
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| Molecular Weight | 211.25800 |
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| Flash Point | 173.9ºC |
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| Exact Mass | 211.12100 |
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| PSA | 53.71000 |
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| LogP | 1.89180 |
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| Index of Refraction | 1.52 |
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| InChIKey | IWXQVPLYQQTJTR-UHFFFAOYSA-N |
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| SMILES | COCCOCCOc1ccc(N)cc1 |
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Synonyms
| iwxqvplyqqtjtr-uhfffaoysa |
| einecs 265-867-1 |
