Introduction：Basic information about CAS 78925-46-9|PEG2-Cl, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | PEG2-Cl |
|---|
| CAS Number | 78925-46-9 | Molecular Weight | 138.593 |
|---|
| Density | 1.1±0.1 g/cm3 | Boiling Point | 236.9±15.0 °C at 760 mmHg |
|---|
| Molecular Formula | C5H11ClO2 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 97.1±20.4 °C |
|---|
Names
| Name | 3-(2-Chloroethoxy)-1-propanol |
|---|
| Synonym | More Synonyms |
|---|
PEG2-Cl BiologicalActivity
| Description | PEG2-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
|---|
| Target | PEGs |
|---|
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|
| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
|---|
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|
| Boiling Point | 236.9±15.0 °C at 760 mmHg |
|---|
| Molecular Formula | C5H11ClO2 |
|---|
| Molecular Weight | 138.593 |
|---|
| Flash Point | 97.1±20.4 °C |
|---|
| Exact Mass | 138.044754 |
|---|
| PSA | 29.46000 |
|---|
| LogP | 0.26 |
|---|
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
|---|
| Index of Refraction | 1.441 |
|---|
| InChIKey | RTYZTARCKASTTM-UHFFFAOYSA-N |
|---|
| SMILES | OCCCOCCCl |
|---|
Synonyms
| 1-Propanol, 3-(2-chloroethoxy)- |
| 3-(2-Chloroethoxy)-1-propanol |
| 3-(2-chloroethoxy)propan-1-ol |
