Introduction：Basic information about CAS 18059-10-4|Peiminine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Peiminine |
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| CAS Number | 18059-10-4 | Molecular Weight | 429.635 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 567.1±50.0 °C at 760 mmHg |
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| Molecular Formula | C27H43NO3 | Melting Point | 212-213ºC |
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| MSDS | / | Flash Point | 296.8±30.1 °C |
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Names
| Name | Peiminine |
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| Synonym | More Synonyms |
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Peiminine BiologicalActivity
| Description | Peiminine(Verticinone; Raddeanine) is a natural compound with anti-inflammatory activity.IC50 value:Target:Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung injury. peiminine inhibits lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury, by reducing circulating IFN-γ levels and inhibiting signal transduction pathways involving TGF-β, CTGF, ERK1/2, NF-κB and FasL. |
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| Related Catalog | Signaling Pathways >>Autophagy >>AutophagyNatural Products >>AlkaloidResearch Areas >>Inflammation/Immunology |
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| References | [1]. Guo H, et al. Peiminine ameliorates bleomycin-induced acute lung injury in rats. Mol Med Rep. 2013 Apr;7(4):1103-10. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 567.1±50.0 °C at 760 mmHg |
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| Melting Point | 212-213ºC |
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| Molecular Formula | C27H43NO3 |
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| Molecular Weight | 429.635 |
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| Flash Point | 296.8±30.1 °C |
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| Exact Mass | 429.324280 |
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| PSA | 60.77000 |
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| LogP | 3.90 |
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| Vapour Pressure | 0.0±3.5 mmHg at 25°C |
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| Index of Refraction | 1.585 |
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| InChIKey | IQDIERHFZVCNRZ-YUYPDVIUSA-N |
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| SMILES | CC1CCC2N(C1)CC1C3CC4C(CC(=O)C5CC(O)CCC54C)C3CCC1C2(C)O |
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Safety Information
Synonyms
| MFCD00210542 |
| (3β)-3,20-Dihydroxycevan-6-one |
| Osnovanine |
| Raddeamine |
| (3β,5α)-3,20-Dihydroxycevan-6-one |
| Cevan-6-one, 3,20-dihydroxy-, (3β,5α)- |
| Sipeimine |
| 3beta,20-Dihydroxy-5alpha-cevan-6-one |
| 3β,20-Dihydroxy-5α-cevan-6-one |
| (3b)-3,20-Dihydroxycevan-6-one |
| RADDEANINE |
| Cevan-6-one, 3,20-dihydroxy-, (3β)- |
| cevan-6-one, 3,20-dihydroxy-, (3b)- |
| PEINININE |
| Fritillarine |
| Verticinone |
