Introduction：Basic information about CAS 7460-43-7|Rubiadin 1-methyl ether, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Rubiadin 1-methyl ether |
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| CAS Number | 7460-43-7 | Molecular Weight | 268.264 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 502.2±50.0 °C at 760 mmHg |
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| Molecular Formula | C16H12O4 | Melting Point | / |
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| MSDS | / | Flash Point | 193.0±23.6 °C |
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Names
| Name | rubiadin 1-methyl ether |
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| Synonym | More Synonyms |
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Rubiadin 1-methyl ether BiologicalActivity
| Description | Rubiadin-1-methyl ether is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65[1]. |
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| Target | p65 |
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| References | [1]. He YQ, et al. Rubiadin-1-methyl ether from Morinda officinalis How. Inhibits osteoclastogenesis through blocking RANKL-induced NF-κB pathway. Biochem Biophys Res Commun. 2018 Dec 2;506(4):927-931. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 502.2±50.0 °C at 760 mmHg |
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| Molecular Formula | C16H12O4 |
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| Molecular Weight | 268.264 |
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| Flash Point | 193.0±23.6 °C |
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| Exact Mass | 268.073547 |
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| PSA | 63.60000 |
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| LogP | 3.92 |
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| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
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| Index of Refraction | 1.649 |
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| InChIKey | NTBUBTCXACOEEC-UHFFFAOYSA-N |
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| SMILES | COc1c(C)c(O)cc2c1C(=O)c1ccccc1C2=O |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2914690090 |
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Customs
| HS Code | 2914690090 |
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| Summary | 2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
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Synonyms
| 9,10-Anthracenedione, 3-hydroxy-1-methoxy-2-methyl- |
| 9,10-Anthracenedione,3-hydroxy-1-methoxy-2-methyl |
| 3-Hydroxy-1-methoxy-2-methylanthraquinone |
| 1,3-dimethoxy-2-methylanthraquinone |
| 3-Hydroxy-1-methoxy-2-methyl-anthraquinone |
| 3-Hydroxy-1-methoxy-2-methyl-9,10-anthraquinone |
| rubiadin-1-methyl ether |
| 3-Hydroxy-1-methoxy-2-methyl-anthrachinon |
