Introduction：Basic information about CAS 6468-55-9|Demethylwedelolactone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Demethylwedelolactone |
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| CAS Number | 6468-55-9 | Molecular Weight | 300.220 |
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| Density | 1.8±0.1 g/cm3 | Boiling Point | 531.4±35.0 °C at 760 mmHg |
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| Molecular Formula | C15H8O7 | Melting Point | 360ºC |
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| MSDS | / | Flash Point | 275.2±25.9 °C |
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Names
| Name | 1,3,8,9-Tetrahydroxy-6H-benzofuro[3,2-c]chromen-6-one |
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| Synonym | More Synonyms |
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Demethylwedelolactone BiologicalActivity
| Description | Demethylwedelolactone is a naturally occurring coumestan isolated from Eclipta alba. Demethylwedelolactone is a potent trypsin inhibitor with an IC50 of 3.0 μM. Demethylwedelolactone suppresses cell motility and cell invasion of breast cancer cell[1][2]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| Target | IC50: 3.0 μM (trypsin)[1] |
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| References | [1]. Syed SD, et al. Trypsin inhibitory effect of wedelolactone and demethylwedelolactone. Phytother Res. 2003 Apr;17(4):420-1. [2]. Lee YJ, et al. Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. Eur J Med Chem. 2012 Oct;56:361-7. |
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Chemical & Physical Properties
| Density | 1.8±0.1 g/cm3 |
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| Boiling Point | 531.4±35.0 °C at 760 mmHg |
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| Melting Point | 360ºC |
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| Molecular Formula | C15H8O7 |
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| Molecular Weight | 300.220 |
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| Flash Point | 275.2±25.9 °C |
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| Exact Mass | 300.027008 |
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| PSA | 124.27000 |
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| LogP | 1.79 |
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| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
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| Index of Refraction | 1.847 |
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| InChIKey | LUTYTNLPIUCKBJ-UHFFFAOYSA-N |
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| SMILES | O=c1oc2cc(O)cc(O)c2c2oc3cc(O)c(O)cc3c12 |
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| Storage condition | 2-8℃ |
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Safety Information
Customs
| HS Code | 2932999099 |
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| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 6H-Benzofuro[3,2-c][1]benzopyran-6-one, 1,3,8,9-tetrahydroxy- |
| 6H-Benzofuro(3,2-c)(1)benzopyran-6-one, 1,3,8,9-tetrahydroxy- |
| 1,3,8,9-Tetrahydroxy-6H-[1]benzofuro[3,2-c]chromen-6-one |
| demethylwedelolactone |
