CAS 23094-69-1|corilagin
| Common Name | corilagin | ||
|---|---|---|---|
| CAS Number | 23094-69-1 | Molecular Weight | 634.453 |
| Density | 2.1±0.1 g/cm3 | Boiling Point | 1280.8±65.0 °C at 760 mmHg |
| Molecular Formula | C27H22O18 | Melting Point | >200ºC dec |
| MSDS | ChineseUSA | Flash Point | 418.8±27.8 °C |
Names
| Name | corilagin |
|---|---|
| Synonym | More Synonyms |
corilagin BiologicalActivity
| Description | Corilagin, a gallotannin, is isolated from Caesalpinia coriaria (Jacq.) Willd. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows good anti-tumor activity on hepatocellular carcinoma and ovarian cancer. Corilagin shows a low level of toxicity toward normal cells and tissues[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerResearch Areas >>InfectionResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Anti-infection >>Reverse TranscriptaseSignaling Pathways >>Anti-infection >>Bacterial |
| References | [1]. Li X, et al. Corilagin, a promising medicinal herbal agent. Biomed Pharmacother. 2018 Mar;99:43-50. |
Chemical & Physical Properties
| Density | 2.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 1280.8±65.0 °C at 760 mmHg |
| Melting Point | >200ºC dec |
| Molecular Formula | C27H22O18 |
| Molecular Weight | 634.453 |
| Flash Point | 418.8±27.8 °C |
| Exact Mass | 634.080627 |
| PSA | 310.66000 |
| LogP | 2.34 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.881 |
| InChIKey | TUSDEZXZIZRFGC-UHFFFAOYSA-N |
| SMILES | O=C(OC1OC2COC(=O)c3cc(O)c(O)c(O)c3-c3c(cc(O)c(O)c3O)C(=O)OC(C2O)C1O)c1cc(O)c(O)c(O)c1 |
| Storage condition | -20°C Freezer |
| Water Solubility | H2O: soluble1mg/mL, clear, colorless |
Safety Information
| RIDADR | NONH for all modes of transport |
|---|
Articles25
More Articles| Mechanisms of action of corilagin and tellimagrandin I that remarkably potentiate the activity of beta-lactams against methicillin-resistant Staphylococcus aureus. Microbiol. Immunol. 48(1) , 67-73, (2004) Corilagin and tellimagrandin I are polyphenols isolated from the extract of Arctostaphylos uvaursi and Rosa canina L. (rose red), respectively. We have reported that corilagin and tellimagrandin I rem... | |
| Inhibitory effect of the gallotannin corilagin on dextran sulfate sodium-induced murine ulcerative colitis. J. Nat. Prod. 76(11) , 2120-5, (2013) The therapeutic effect of corilagin (1) was evaluated in an acute colitis model induced by dextran sulfate sodium (DSS) in mice, and the mechanism of action was investigated in this study. Animals wer... | |
| Modulation of PAI-1 and tPA activity and thrombolytic effects of corilagin. Planta Med. 69(12) , 1109-12, (2003) In this study, Charlton's and Tomihisa's methods were modified to investigate the thrombolytic effect of corilagin from the Chinese herbal plant Phyllanthus urinaria L., as well as its effect on carot... |
Synonyms
| Benzoic acid, 3,4,5-trihydroxy-, (8R,10S,11R,12S,19R)-5,7,8,11,12,14-hexahydro-1,2,3,11,16,17,18,19-octahydroxy-5,14-dioxo-8,12-methano-10H-dibenzo[j,l][1,4,8]trioxacyclotetradecin-10-yl ester |
| (1S,19R,21S,22R,23R)-6,7,8,11,12,13,22,23-Octahydroxy-3,16-dioxo-2,17,20-trioxatetracyclo[17.3.1.0.0]tricosa-4,6,8,10,12,14-hexaen-21-yl 3,4,5-trihydroxybenzoate |
| corilagin |
| 1-O-Galloyl-3,6-hexahydroxydiphenol-b-D-Glucopyranose |
| 1-O-Galloyl-3,6-hexahydroxydiphenol--D-Glucopyranose |
