CAS 6419-19-8|Aminotrimethylene phosphonic acid

Introduction：Basic information about CAS 6419-19-8|Aminotrimethylene phosphonic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles14
7. Synonyms

Common Name	Aminotrimethylene phosphonic acid
CAS Number	6419-19-8	Molecular Weight	299.050
Density	2.1±0.1 g/cm3	Boiling Point	746.2±70.0 °C at 760 mmHg
Molecular Formula	C₃H₁₂NO₉P₃	Melting Point	~215 °C (dec.)
MSDS	ChineseUSA	Flash Point	405.1±35.7 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	Amino tris(methylene phosphonic acid)
Synonym	More Synonyms

Chemical & Physical Properties

Density	2.1±0.1 g/cm3
Boiling Point	746.2±70.0 °C at 760 mmHg
Melting Point	~215 °C (dec.)
Molecular Formula	C₃H₁₂NO₉P₃
Molecular Weight	299.050
Flash Point	405.1±35.7 °C
Exact Mass	298.972504
PSA	205.26000
LogP	-4.63
Vapour Pressure	0.0±5.4 mmHg at 25°C
Index of Refraction	1.610
InChIKey	YDONNITUKPKTIG-UHFFFAOYSA-N
SMILES	O=P(O)(O)CN(CP(=O)(O)O)CP(=O)(O)O
Stability	Stable. Incompatible with bases, strong oxidizing agents.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SZ9860000

CHEMICAL NAME :: Phosphonic acid, (nitrilotris(methylene))tri-

CAS REGISTRY NUMBER :: 6419-19-8

BEILSTEIN REFERENCE NO. :: 1715724

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C3-H12-N-O9-P3

MOLECULAR WEIGHT :: 299.07

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0990-0937

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0990-0937 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(2),67,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >6310 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0990-0937

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: >2510 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0990-0937

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: >2510 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0990-0937 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1302 mg/kg/31D-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition Nutritional and Gross Metabolic - weight loss or decreased weight gain Nutritional and Gross Metabolic - changes in sodium

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(2),67,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1717 No. of Facilities: 72 (estimated) No. of Industries: 5 No. of Occupations: 7 No. of Employees: 1279 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1717 No. of Facilities: 2426 (estimated) No. of Industries: 57 No. of Occupations: 33 No. of Employees: 38609 (estimated) No. of Female Employees: 2280 (estimated)

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	C:Corrosive
Risk Phrases	R34
Safety Phrases	S26-S45-S36/37/39-S25
RIDADR	3265
WGK Germany	1
RTECS	SZ9860000
Packaging Group	III
Hazard Class	8
HS Code	2931900090

Customs

HS Code	2931900090
Summary	2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Articles14

Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase.

Proc. Natl. Acad. Sci. U. S. A. 104 , 12282-7, (2007)

Conjugative transfer of plasmid DNA via close cell-cell junctions is the main route by which antibiotic resistance genes spread between bacterial strains. Relaxases are essential for conjugative trans...

Determination of phosphonates in natural waters by ion-pair high-performance liquid chromatography.

J. Chromatogr. A. 773(1-2) , 139-46, (1997)

The paper describes a new method for the determination of phosphonates by ion-pair high-performance liquid chromatography. The phosphonates are complexed with Fe(III) and separated on a reversed-phase...

Adsorptive removal of nitrilotris(methylenephosphonic acid) antiscalant from membrane concentrates by iron-coated waste filtration sand.

J. Hazard. Mater. 182(1-3) , 855-62, (2010)

Iron-coated waste filtration sand was investigated as a low-cost adsorbent for the removal of nitrilotris(methylenephosphonic acid) (NTMP) from membrane concentrates. The adsorption of this phosphonat...

Synonyms

Aminotri(methylene phosphonic acid)

nitrilotrimethylenephosphonic acid

N,N,N-triphosphonomethyl amine

Aminotris(methylphosphonic acid)

[Nitrilotris(methylene)]tris(phosphonic acid)

N_Tf

(Nitrilotris(methylene))triphosphonic acid

ATMP

ferrofos509

ATMPA

(nitrilotrimethanediyl)tris(phosphonic acid)

UNII-1Y702GD0FG

dowelll37

ntpo

Dequest 2000

BRIQUEST 301-50A

Aminotris(methanephosphonic acid)

Briquest 301

EINECS 229-146-5

MFCD00002138

Amino tris(methylene phosphonic acid)

Phosphonic acid, [nitrilotris(methylene)]tris-

Amino tris (methylene phosphonic acid)

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