Introduction：Basic information about CAS 496-65-1|(R)-Pantetheine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (R)-Pantetheine |
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| CAS Number | 496-65-1 | Molecular Weight | 278.36800 |
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| Density | 1.202g/cm3 | Boiling Point | 635ºC at 760mmHg |
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| Molecular Formula | C11H22N2O4S | Melting Point | / |
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| MSDS | / | Flash Point | 337.8ºC |
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Names
| Name | pantetheine |
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| Synonym | More Synonyms |
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(R)-Pantetheine BiologicalActivity
| Description | (R)-Pantetheine is the biosynthetic precursor to CoA.(R)-Pantetheine and its corresponding disulfide pantethine, play a key role in metabolism as a building block of coenzyme A (CoA)[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
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| References | [1]. Rothmann M, et al. Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A. J Am Chem Soc. 2013 Apr 24;135(16):5962-5. |
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Chemical & Physical Properties
| Density | 1.202g/cm3 |
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| Boiling Point | 635ºC at 760mmHg |
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| Molecular Formula | C11H22N2O4S |
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| Molecular Weight | 278.36800 |
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| Flash Point | 337.8ºC |
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| Exact Mass | 278.13000 |
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| PSA | 137.46000 |
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| Vapour Pressure | 8.53E-19mmHg at 25°C |
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| Index of Refraction | 1.526 |
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| InChIKey | ZNXZGRMVNNHPCA-VIFPVBQESA-N |
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| SMILES | CC(C)(CO)C(O)C(=O)NCCC(=O)NCCS |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- ES4316750
- CHEMICAL NAME :
- Butyramide, 2,4-dihydroxy-N-(2-((2-mercaptoethyl)carbamoyl)ethyl) -3,3-dimethyl-
- CAS REGISTRY NUMBER :
- 496-65-1
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C11-H22-N2-O4-S
- MOLECULAR WEIGHT :
- 278.41
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 440 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- RAREAE Radiation Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1954- Volume(issue)/page/year: 7,13,1957
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Safety Information
| Hazard Codes | T |
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| Risk Phrases | 25 |
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| Safety Phrases | 45 |
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| RIDADR | UN 2811 6.1 / PGIII |
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Synonyms
| (2R)-2,4-Dihydroxy-N-[2-[(2-mercaptoethyl)carbamoyl]ethyl]-3,3-dimethylbutyramide |
| Lactobacillusbulgaricusfactor |
| pantethine,Bis(N-pantothenylamidoethyl) disulfide |
| D-pantothenic acid-(2-mercapto-ethylamide) |
| D-N-pantothenylamidoethyl mercaptan |
| 2,4-dihydroxy-3,3-dimethyl-N-[2-(2-sulfanylethylcarbamoyl)ethyl]butanamide |
| (R)-2,4-Dihydroxy-N-[3-[(2-mercaptoethyl)amino]-3-oxopropyl]-3,3-dimethylbutanamide |
| (R)-2,4-dihydroxy-N-[3-[(2-mercaptoethyl)amino]-3-oxopropyl]-3,3-dimethylbutyramide |
| Pantetheine |
