CAS 34803-66-2|1-(2-Pyridinyl)piperazine
Introduction：Basic information about CAS 34803-66-2|1-(2-Pyridinyl)piperazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 1-(2-Pyridinyl)piperazine | ||
|---|---|---|---|
| CAS Number | 34803-66-2 | Molecular Weight | 163.22 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 314.4±22.0 °C at 760 mmHg |
| Molecular Formula | C9H13N3 | Melting Point | 92-94 |
| MSDS | ChineseUSA | Flash Point | 143.9±22.3 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 1-pyridin-2-ylpiperazine |
|---|---|
| Synonym | More Synonyms |
1-(2-Pyridinyl)piperazine BiologicalActivity
| Description | 1-(2-Pyridyl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
|---|---|
| Related Catalog | Research Areas >>Others |
| In Vitro | 1-(2-Pyridyl)piperazine 是一种选择性的 α2-肾上腺素能受体拮抗剂。它显示出同情活动。它也是 Azaperone 的代谢产物。 |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 314.4±22.0 °C at 760 mmHg |
| Melting Point | 92-94 |
| Molecular Formula | C9H13N3 |
| Molecular Weight | 163.22 |
| Flash Point | 143.9±22.3 °C |
| Exact Mass | 163.110947 |
| PSA | 28.16000 |
| LogP | 0.19 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.547 |
| InChIKey | GZRKXKUVVPSREJ-UHFFFAOYSA-N |
| SMILES | c1ccc(N2CCNCC2)nc1 |
| Storage condition | Flammables area |
| Water Solubility | >500 g/L (20 ºC) |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | 2735 |
| WGK Germany | 3 |
| Packaging Group | II |
| Hazard Class | 8 |
| HS Code | 2933990090 |
Customs
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles8
More Articles| Pharmacological evidence for the involvement of 1-(2-pyridinyl)-piperazine (1-PmP) in the interaction of buspirone or gepirone with noradrenergic systems. Eur. J. Pharmacol. 134(1) , 113-6, (1987) We investigated in mice the effects of one of the principal metabolites of buspirone and gepirone, 1-(2-pyridinyl)-piperazine (1-PmP), on hypothermia and reduced locomotion induced by clonidine (0.25 ... | |
| 6-Hydroxybuspirone is a major active metabolite of buspirone: assessment of pharmacokinetics and 5-hydroxytryptamine1A receptor occupancy in rats. Drug Metab. Dispos. 35(8) , 1387-92, (2007) The pharmacokinetics and in vivo potency of 6-hydroxybuspirone (6-OH-buspirone), a major metabolite of buspirone, were investigated. The plasma clearance (47.3 +/- 3.5 ml/min/kg), volume of distributi... | |
| New lithocholic and chenodeoxycholic piperazinylcarboxamides with antiproliferative and pro-apoptotic effects on human cancer cell lines. Bioorg. Med. Chem. 16 , 8737-44, (2008) Six new synthetic bile acid derivatives were synthesized and tested in vitro against various human cancer cells (glioblastoma multiforme (GBM), multiple myeloma (KMS-11), and colonic carcinoma (HCT-11... |
Synonyms
| 2-(1-Piperazinyl)pyridine |
| 1-(pyridin-2-yl)piperazine |
| 2-Piperazinopyridine |
| 1-(2-Pyridinyl)piperazine |
| Piperazine, 1-(2-pyridinyl)- |
| MFCD00006216 |
| EINECS 252-220-3 |
| 2-pyridylpiperazine |
| 1-(2-Pyridyl)Piperazine |
