CAS 26048-05-5|beauvericin
| Common Name | beauvericin | ||
|---|---|---|---|
| CAS Number | 26048-05-5 | Molecular Weight | 783.949 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 975.6±65.0 °C at 760 mmHg |
| Molecular Formula | C45H57N3O9 | Melting Point | 93-94℃ |
| MSDS | ChineseUSA | Flash Point | 543.8±34.3 °C |
Names
| Name | beauvericin |
|---|---|
| Synonym | More Synonyms |
beauvericin BiologicalActivity
| Description | Beauvericin is a Fusarium mycotoxin. Beauvericin inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 3 μM in an enzyme assay using rat liver microsomes[1]. |
|---|---|
| Related Catalog | Research Areas >>Cardiovascular DiseaseResearch Areas >>InfectionSignaling Pathways >>Metabolic Enzyme/Protease >>Acyltransferase |
| Target | ACAT |
| References | [1]. Tomoda H, et al. Inhibition of acyl-CoA: cholesterol acyltransferase activity by cyclodepsipeptide antibiotics. J Antibiot (Tokyo). 1992 Oct;45(10):1626-32. |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 975.6±65.0 °C at 760 mmHg |
| Melting Point | 93-94℃ |
| Molecular Formula | C45H57N3O9 |
| Molecular Weight | 783.949 |
| Flash Point | 543.8±34.3 °C |
| Exact Mass | 783.409485 |
| PSA | 139.83000 |
| LogP | 5.49 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.530 |
| InChIKey | GYSCAQFHASJXRS-UHFFFAOYSA-N |
| SMILES | CC(C)C1OC(=O)C(Cc2ccccc2)N(C)C(=O)C(C(C)C)OC(=O)C(Cc2ccccc2)N(C)C(=O)C(C(C)C)OC(=O)C(Cc2ccccc2)N(C)C1=O |
| Storage condition | 2-8°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles41
More Articles| Toxicity induced by F. poae-contaminated feed and the protective effect of Montmorillonite supplementation in broilers. Food Chem. Toxicol. 74 , 120-30, (2014) The T-2 and HT-2 toxins, the main metabolites of Fusarium poae, induce toxicity in broilers and accumulate in tissues. Consequently, during the breeding process of broilers, diets are frequently suppl... | |
| Development and validation of an UHPLC-MS/MS method for the determination of mycotoxins in grass silages. Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 32 , 2101-12, (2015) An ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) multi-mycotoxin analytical method was developed to simultaneously identify and quantify 20 mycotoxins in grass si... | |
| Determination of the Mycotoxin Content in Distiller's Dried Grain with Solubles Using a Multianalyte UHPLC-MS/MS Method. J. Agric. Food Chem. 63 , 9441-51, (2015) There are more than 300 potential mycotoxins that can contaminate food and feed and cause adverse effects in humans and animals. The data on the co-occurrence of mycotoxins in novel animal feed materi... |
Synonyms
| 1,7,13-Trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone, 4,10,16-trimethyl-6,12,18-tris(1-methylethyl)-3,9,15-tris(phenylmethyl)-, (3S,6R,9S,12R,15S,18R)- |
| beauvericin |
| BEAUVERFICIN |
| Cyclo(-D-a-hydroxyisovaleryl-N-Me-Phe)3 |
| beauverin |
| (3S,6R,9S,12R,15S,18R)-3,9,15-Tribenzyl-6,12,18-triisopropyl-4,10,16-trimethyl-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone |
| MFCD00056846 |
| (3S,6R,9S,12R,15S,18R)-3,9,15-tribenzyl-6,12,18-tri(propan-2-yl)-4,10,16-trimethyl-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone |
| beauverin bassiaua vuillemin |
| bovein |
