CAS 642928-07-2|Homo Sildenafil

Introduction：Basic information about CAS 642928-07-2|Homo Sildenafil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Homo Sildenafil BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Homo Sildenafil
CAS Number	642928-07-2	Molecular Weight	488.603
Density	1.4±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₂₃H₃₂N₆O₄S	Melting Point	200-202ºC
MSDS	/	Flash Point	/

Names

Name	5-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one
Synonym	More Synonyms

Homo Sildenafil BiologicalActivity

Description	Homo Sildenafil, an analog of Sildenafil, acts as a phosphodiesterase inhibitor[1].
Related Catalog	Research Areas >>EndocrinologySignaling Pathways >>Metabolic Enzyme/Protease >>Phosphodiesterase (PDE)
References	[1]. Jackie D Corbin, et al. Vardenafil: Structural Basis for Higher Potency Over Sildenafil in Inhibiting cGMP-specific phosphodiesterase-5 (PDE5). Neurochem Int. 2004 Nov;45(6):859-63.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Melting Point	200-202ºC
Molecular Formula	C₂₃H₃₂N₆O₄S
Molecular Weight	488.603
Exact Mass	488.220581
PSA	121.80000
LogP	2.80
Index of Refraction	1.656
Storage condition	-20 °C

Synonyms

5-[2-ETHOXY-5-[(4-ETHYL-(PIPERAZIN-1-YL))SULFONYL]PHENYL]-1,6-DIHYDRO-1-METHYL-3-PROPYL-7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE

5-[2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one

PYR397

5-[2-ethoxy-5-(4-ethylpiperazine-1-yl-sulphonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-

Homo Sildenafil

5-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

UNII-0Z3JH0S0QK

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