CAS 977-79-7|Medrogestone

Introduction：Basic information about CAS 977-79-7|Medrogestone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Synonyms

Common Name	Medrogestone
CAS Number	977-79-7	Molecular Weight	340.49900
Density	1.08g/cm3	Boiling Point	467.2ºC at 760mmHg
Molecular Formula	C₂₃H₃₂O₂	Melting Point	/
MSDS	/	Flash Point	173.7ºC

Names

Name	Medrogestone
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.08g/cm3
Boiling Point	467.2ºC at 760mmHg
Molecular Formula	C₂₃H₃₂O₂
Molecular Weight	340.49900
Flash Point	173.7ºC
Exact Mass	340.24000
PSA	34.14000
LogP	5.27970
Index of Refraction	1.549
InChIKey	HCFSGRMEEXUOSS-JXEXPEPMSA-N
SMILES	CC(=O)C1(C)CCC2C3C=C(C)C4=CC(=O)CCC4(C)C3CCC21C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU3832300

CHEMICAL NAME :: Pregna-4,6-diene-3,20-dione, 6,17-dimethyl-

CAS REGISTRY NUMBER :: 977-79-7

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C23-H32-O2

MOLECULAR WEIGHT :: 340.55

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 850 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4230702 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 20500 ug/kg

SEX/DURATION :: female 1 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

REFERENCE :: JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 12,473,1966

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 300 mg/kg

SEX/DURATION :: female 15-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - urogenital system

REFERENCE :: JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 12,473,1966

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 26250 ug/kg

SEX/DURATION :: female 21 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 12,473,1966

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 7500 ug/kg

SEX/DURATION :: female 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

REFERENCE :: JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 12,473,1966

Synonyms

EINECS 213-555-0

4,6-PREGNADIEN-6,17-DIMETHYL-3,20-DIONE

6,17-Dimethyl-4,6-pregnadien-3.20-dion

MFCD00271888

6,17-Dimethyl-pregnadien-(4,6)-dion-(3.20)

6,17-Dimethyl-pregna-4,6-dien-3.20-dion

6,17-dimethylpregna4,6-diene-3,20-dione

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