CAS 65914-17-2|(E/Z)-Polydatin
| Common Name | (E/Z)-Polydatin | ||
|---|---|---|---|
| CAS Number | 65914-17-2 | Molecular Weight | 407.39100 |
| Density | 1.521 g/cm3 | Boiling Point | 707.7ºC at 760 mmHg |
| Molecular Formula | C20H22O8 | Melting Point | 223-226 °C(lit.) |
| MSDS | USA | Flash Point | 381.8ºC |
Names
| Name | (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol |
|---|---|
| Synonym | More Synonyms |
(E/Z)-Polydatin BiologicalActivity
| Description | (E/Z)-Polydatin ((E/Z)-Piceid) is a monocrystalline compound originally isolated from the root and rhizome of Polygonum cuspidatum. (E/Z)-Polydatin has anti-platelet aggregation, anti-oxidative action of low-density lipoprotein (LDL), cardioprotective activity, anti-inflammatory and immune-regulating functions[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
| References | [1]. Du QH, et al. Polydatin: a review of pharmacology and pharmacokinetics. Pharm Biol. 2013 Nov;51(11):1347-54. |
Chemical & Physical Properties
| Density | 1.521 g/cm3 |
|---|---|
| Boiling Point | 707.7ºC at 760 mmHg |
| Melting Point | 223-226 °C(lit.) |
| Molecular Formula | C20H22O8 |
| Molecular Weight | 407.39100 |
| Flash Point | 381.8ºC |
| Exact Mass | 407.13400 |
| PSA | 160.07000 |
| LogP | 0.49640 |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles30
More Articles| Protective effect of polydatin against burn-induced lung injury in rats. Respir. Care 59(9) , 1412-21, (2014) Polydatin (PD) has anti-inflammatory and anti-apoptotic effects in ischemic-reperfusion injury. Moreover, inflammatory responses and apoptosis play a role in the development of burn-induced lung injur... | |
| Nephroprotective Effects of Polydatin against Ischemia/Reperfusion Injury: A Role for the PI3K/Akt Signal Pathway. Oxid. Med. Cell. Longev. 2015 , 362158, (2015) Oxidative stress and inflammation are involved in the pathogenesis in renal ischemia/reperfusion (I/R) injury. It has been demonstrated that polydatin processed the antioxidative, anti-inflammatory, a... | |
| Pre-column incubation followed by fast liquid chromatography analysis for rapid screening of natural methylglyoxal scavengers directly from herbal medicines: case study of Polygonum cuspidatum. J. Chromatogr. A. 1286 , 102-10, (2013) Methylglyoxal (MGO), a very reactive metabolite of glucose, plays a pivotal role in the pathogenesis of several chronic diseases associated with diabetes, and it has been validated as an attractive ta... |
Synonyms
| 3,4,5-Tsg |
| trans-polydatin |
| MFCD00210592 |
| (E)-Polydatin |
| Trans-Piceid |
| Giant knotweed Extract |
| Piceid |
| Reservatrol-3-β-mono-D-glucoside |
| Polydatin |
