CAS 92-39-7|2-Chlorophenothiazine
Introduction：Basic information about CAS 92-39-7|2-Chlorophenothiazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Chlorophenothiazine | ||
|---|---|---|---|
| CAS Number | 92-39-7 | Molecular Weight | 233.717 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 395.7±31.0 °C at 760 mmHg |
| Molecular Formula | C12H8ClNS | Melting Point | 195-200 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 193.1±24.8 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 2-Chlorophenothiazine |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 395.7±31.0 °C at 760 mmHg |
| Melting Point | 195-200 °C(lit.) |
| Molecular Formula | C12H8ClNS |
| Molecular Weight | 233.717 |
| Flash Point | 193.1±24.8 °C |
| Exact Mass | 233.006592 |
| PSA | 37.33000 |
| LogP | 5.18 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.680 |
| InChIKey | KFZGLJSYQXZIGP-UHFFFAOYSA-N |
| SMILES | Clc1ccc2c(c1)Nc1ccccc1S2 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 18 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 160 mg/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 26,1205,1977
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 160 mg/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 26,1205,1977
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36-S37/39 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | SN7580000 |
| Hazard Class | 6.1 |
| HS Code | 2934300000 |
Customs
| HS Code | 2934300000 |
|---|---|
| Summary | 2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles8
More Articles| Reversing the Warburg effect as a treatment for glioblastoma. J. Biol. Chem. 288(13) , 9153-64, (2013) Glioblastoma multiforme (GBM), like most cancers, possesses a unique bioenergetic state of aerobic glycolysis known as the Warburg effect. Here, we documented that methylene blue (MB) reverses the War... | |
| Broad specific enzyme-linked immunosorbent assay for determination of residual phenothiazine drugs in swine tissues. Anal. Biochem. 454 , 7-13, (2014) In this study, a novel generic hapten of phenothiazine drugs was synthesized by derivatization of 2-chlorophenothiazine with sodium bromoacetate. Then the hapten was coupled to bovine serum albumin fo... | |
| N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J. Med. Chem. 54 , 4247-63, (2011) A total of 53 N-benzoylated phenoxazines and phenothiazines, including their S-oxidized analogues, were synthesized and evaluated for antiproliferative activity, interaction with tubulin, and cell cyc... |
Synonyms
| EINECS 202-152-5 |
| 10H-Phenothiazine, 2-chloro- |
| 2-Chloro-10H-phenothiazine |
| MFCD00005016 |
