CAS 920-37-6|2-Chloroacrylonitrile
Introduction：Basic information about CAS 920-37-6|2-Chloroacrylonitrile, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Chloroacrylonitrile | ||
|---|---|---|---|
| CAS Number | 920-37-6 | Molecular Weight | 87.508 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 89.5±13.0 °C at 760 mmHg |
| Molecular Formula | C3H2ClN | Melting Point | −65 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 6.7±0.0 °C |
| Symbol | GHS02, GHS05, GHS06, GHS08, GHS09 | Signal Word | Danger |
Names
| Name | 2-Chloroacrylonitrile |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 89.5±13.0 °C at 760 mmHg |
| Melting Point | −65 °C(lit.) |
| Molecular Formula | C3H2ClN |
| Molecular Weight | 87.508 |
| Flash Point | 6.7±0.0 °C |
| Exact Mass | 86.987579 |
| PSA | 23.79000 |
| LogP | 0.34 |
| Vapour Pressure | 58.4±0.2 mmHg at 25°C |
| Index of Refraction | 1.435 |
| InChIKey | OYUNTGBISCIYPW-UHFFFAOYSA-N |
| SMILES | C=C(Cl)C#N |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Vascular - regional or general arteriolar or venous dilation Skin and Appendages - hair
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555346
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 304 mg/m3/6H
- TOXIC EFFECTS :
- Vascular - regional or general arteriolar or venous dilation Lungs, Thorax, or Respiration - dyspnea Skin and Appendages - hair
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555346
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Vascular - regional or general arteriolar or venous dilation Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555346
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Skin and Appendages - hair
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555346
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 105 mg/m3/2H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 27(2),52,1983
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - tremor Skin and Appendages - hair
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555346
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02164
Safety Information
| Symbol | GHS02, GHS05, GHS06, GHS08, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H300 + H310 + H330-H314-H334-H350-H400 |
| Precautionary Statements | P201-P210-P260-P280-P284-P301 + P310 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P308 + P313-P403 + P233 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | F:Flammable |
| Risk Phrases | R11;R23/24;R28;R36/37/38;R40 |
| Safety Phrases | S53-S26-S36/37/39-S45-S61-S28A-S16-S1 |
| RIDADR | UN 3383 6.1/PG 1 |
| WGK Germany | 3 |
| RTECS | AT5525000 |
| Packaging Group | II |
| Hazard Class | 3.1 |
| HS Code | 2926909090 |
Customs
| HS Code | 2926909090 |
|---|---|
| Summary | HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Articles9
More Articles| Structure-nephrotoxicity relationships of glutathione pathway intermediates derived from organic solvents. Toxicology 56(1) , 47-61, (1989) The nephrotoxicity of glutathione (GSH) pathway metabolites derived from toluene (TOL), styrene (STYR), bromobenzene (BB), acrylonitrile (ACLN) and 2-chloroacrylonitrile (CACLN) were compared with tha... | |
| [Information from the Soviet Toxicology Center]. Gig. Tr. Prof. Zabol. (2) , 52-3, (1983) | |
| Dual-function cinchona alkaloid catalysis: catalytic asymmetric tandem conjugate addition-protonation for the direct creation of nonadjacent stereocenters. J. Am. Chem. Soc. 128(12) , 3928-30, (2006) Catalytic tandem asymmetric reactions constitute a powerful strategy for the asymmetric construction of nonadjacent stereocenters in acyclic molecules directly from achiral precursors. In this Communi... |
Synonyms
| 2-chloro-acrylonitrile |
| 2-CHLOROCYANOETHYLENE |
| 1-Chloroaerylonitrile |
| MFCD00001858 |
| 2-PROPENONITRLLE |
| Chloroacrylonitrile |
| 2-Propenenitrile, 2-chloro- |
| 2-chloro-acrylonitril |
| NCYGU1 |
| 2-Chloroacrylonitrile |
| β-Chloroacrylonitrile |
| 2-CHLORACRYLONITRIL |
| EINECS 213-055-2 |
| 2-Chloroprop-2-enenitrile |
| 1-Cyanovinyl chloride |
| 2-chloroacrylnitrile |
