Introduction：Basic information about CAS 28189-85-7|Piperidine,2-[(2S,4S)-2-ethyl-2-phenyl-1,3-dioxolan-4-yl]-, (2S)-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Piperidine,2-[(2S,4S)-2-ethyl-2-phenyl-1,3-dioxolan-4-yl]-, (2S)- |
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| CAS Number | 28189-85-7 | Molecular Weight | 261.35900 |
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| Density | 1.057g/cm3 | Boiling Point | 373ºC at 760mmHg |
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| Molecular Formula | C16H23NO2 | Melting Point | / |
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| MSDS | / | Flash Point | 157.4ºC |
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Names
| Name | 2-(2-ethyl-2-phenyl-1,3-dioxolan-4-yl)piperidine |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Etoxadrol is a potent N-methyl-D-aspartic acid (NMDA) antagonist with high affinity. Etoxadrol can be used for anaesthetic research[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| Target | NMDA[1] |
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| In Vivo | Etoxadrol (100.0 mg/kg; i.h.; 30 min) produces marked stimulation and ataxia in mice[2]. Animal Model: Carworth-Farm (Upjohn) male mice weighing 18 to 20 gm[2] Dosage: 100.0 mg/kg Administration: Subcutaneous injection, 30 min Result: Produced marked stimulation and ataxia. |
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| References | [1]. A Thurkauf, et al. Synthesis, absolute configuration, and molecular modeling study of etoxadrol, a potent phencyclidine-like agonist. J Med Chem. 1988 Dec;31(12):2257-63. [2]. A H Tang, et al. Analgetic activities of etoxadrol in the rhesus monkey and in mice. Anesth Analg. 1973 Jul-Aug;52(4):577-83. |
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Chemical & Physical Properties
| Density | 1.057g/cm3 |
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| Boiling Point | 373ºC at 760mmHg |
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| Molecular Formula | C16H23NO2 |
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| Molecular Weight | 261.35900 |
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| Flash Point | 157.4ºC |
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| Exact Mass | 261.17300 |
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| PSA | 30.49000 |
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| LogP | 3.13570 |
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| Index of Refraction | 1.52 |
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| InChIKey | INOYCBNLWYEPSB-UHFFFAOYSA-N |
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| SMILES | CCC1(c2ccccc2)OCC(C2CCCCN2)O1 |
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Safety Information
Customs
| HS Code | 2933399090 |
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| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| CL-1848C |
| Piperidine,3-dioxolan-4-yl) |
| ETOXADROL |
