CAS 76145-76-1|Tomoxiprole

Introduction:Basic information about CAS 76145-76-1|Tomoxiprole, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameTomoxiprole
CAS Number76145-76-1Molecular Weight316.39600
Density1.178g/cm3Boiling Point529.1ºC at 760 mmHg
Molecular FormulaC21H20N2OMelting Point/
MSDS/Flash Point186.5ºC

Names

Name2-(4-methoxyphenyl)-3-propan-2-ylbenzo[e]benzimidazole
SynonymMore Synonyms

Chemical & Physical Properties

Density1.178g/cm3
Boiling Point529.1ºC at 760 mmHg
Molecular FormulaC21H20N2O
Molecular Weight316.39600
Flash Point186.5ºC
Exact Mass316.15800
PSA27.05000
LogP5.44600
Index of Refraction1.666
InChIKeyXVDXNSRMHBAVAX-UHFFFAOYSA-N
SMILESCOc1ccc(-c2nc3c4ccccc4ccc3n2C(C)C)cc1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QK9343000
CHEMICAL NAME :
3H-Naphth(1,2-d)imidazole, 2-(4-methoxyphenyl)-3-(1-methylethyl)-
CAS REGISTRY NUMBER :
76145-76-1
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C21-H20-N2-O
MOLECULAR WEIGHT :
316.43
WISWESSER LINE NOTATION :
T B566 CN ENJ DR DO1& EY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJDPD2 European Journal of Drug Metabolism and Pharmacokinetics. (Medecine et Hygiene, POB 229, CH-1211 Geneva 4, Switzerland) V.1- 1976- Volume(issue)/page/year: 10,161,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,133,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,133,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,133,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,133,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,133,1985

Safety Information

HS Code2933990090

Customs

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

Tomoxiprolum
S085
3-(1-methylethyl)-2-(4-methoxyphenyl)-3H-naphth<1,2-d>imidazole
UNII-EZ948T2878
Tomoxiprole
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