CAS 17278-28-3|Isocucurbitacin B

Introduction：Basic information about CAS 17278-28-3|Isocucurbitacin B, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameIsocucurbitacin B
CAS Number17278-28-3Molecular Weight558.703
Density1.2±0.1 g/cm3Boiling Point702.4±60.0 °C at 760 mmHg
Molecular FormulaC32H46O8Melting Point/
MSDS/Flash Point219.9±26.4 °C

Names

Name[(E,6R)-6-[(3S,8S,9R,10R,13R,14S,16R,17R)-3,16-dihydroxy-4,4,9,13,14-pentamethyl-2,11-dioxo-3,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate
SynonymMore Synonyms

Isocucurbitacin B BiologicalActivity

DescriptionIsocucurbitacin B is a potent cytotoxic compound isolated from Helicteres rswa L. (Sterculiaceae). Isocucurbitacin B possesses anti-tumor acticity[1][2].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Others >>Others
References

[1]. MF Bean, et al. Cucurbitacin B and isocucurbitacin B: cytotoxic components of Helicteres isora. Journal of Natural Products. 1985.

[2]. SM Kupchan, et al. Tumor Inhibitors. XXIII.1 The Cytotoxic Principles of Marah oreganus.H. Cytotoxic principles of Marah oreganus H. 1976.

Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point702.4±60.0 °C at 760 mmHg
Molecular FormulaC32H46O8
Molecular Weight558.703
Flash Point219.9±26.4 °C
Exact Mass558.319275
PSA138.20000
LogP2.06
Vapour Pressure0.0±5.0 mmHg at 25°C
Index of Refraction1.568
InChIKeyWTBZNVRBNJWSPF-DZEACCAPSA-N
SMILESCC(=O)OC(C)(C)C=CC(=O)C(C)(O)C1C(O)CC2(C)C3CC=C4C(CC(=O)C(O)C4(C)C)C3(C)C(=O)CC12C

Synonyms

(1S,4R,9β,16α,23E)-1,16,20-Trihydroxy-9,10,14-trimethyl-2,11,22-trioxo-4,9-cyclo-9,10-secocholesta-5,23-dien-25-yl acetate
Isocucurbitacin B
2-EPICUCURBITICIN B
CUCURBITCIN B,2-EPI
Estr-5-ene-2,11-dione, 17-[(1R,3E)-5-(acetyloxy)-1-hydroxy-1,5-dimethyl-2-oxo-3-hexen-1-yl]-3,16-dihydroxy-4,4,9,14-tetramethyl-, (3α,9β,10α,16α,17β)-
19-Norlanosta-5,23-diene-2,11,22-trione, 25-(acetyloxy)-3,16,20-trihydroxy-9-methyl-, (3α,9β,10α,16α,23E)-
CAS 14682-46-3|Azuleno[6,5-b]furan-2(3H)-one,7-(acetyloxy)-3a,4,4a,5,6,7,7a,9a-octahydro-5-hy
CAS 10300-27-3|Guanosine, 3'-O-methyl-
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