CAS 10300-27-3|Guanosine, 3'-O-methyl-

Introduction:Basic information about CAS 10300-27-3|Guanosine, 3'-O-methyl-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameGuanosine, 3'-O-methyl-
CAS Number10300-27-3Molecular Weight297.26700
Density1.98g/cm3Boiling Point711.7ºC at 760mmHg
Molecular FormulaC11H15N5O5Melting Point/
MSDS/Flash Point384.2ºC

Names

Name3'-O-methylguanosine
SynonymMore Synonyms

Guanosine, 3'-O-methyl- BiologicalActivity

Description3'-O-Methylguanosine is a methylated nucleoside analogs and a RNA chain terminator. 3'-O-methylguanosine can inhibit early virus-specific RNA synthesis[1].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
Target

Human Endogenous Metabolite

References

[1]. B B Goswami, et al. Inhibition of vaccinia virus growth and virus-specific RNA synthesis by 3'-O-methyl adenosine and 3'-O-methyl guanosine. J Virol. 1983 Mar;45(3):1164-7.

Chemical & Physical Properties

Density1.98g/cm3
Boiling Point711.7ºC at 760mmHg
Molecular FormulaC11H15N5O5
Molecular Weight297.26700
Flash Point384.2ºC
Exact Mass297.10700
PSA148.51000
Vapour Pressure2.93E-21mmHg at 25°C
Index of Refraction1.829
InChIKeyUYARPHAXAJAZLU-KQYNXXCUSA-N
SMILESCOC1C(CO)OC(n2cnc3c(=O)[nH]c(N)nc32)C1O

Safety Information

Hazard CodesXi

Synonyms

2-amino-9-[3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]-3H-purin-6-one
3'-O-methyl-guanosine
3'-O-Methylguanosin
3'-OMe-G
O3'-methyl-guanosine
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