Introduction：Basic information about CAS 82845-85-0|5-Methyluridine-d4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-Methyluridine-d4 |
|---|
| CAS Number | 82845-85-0 | Molecular Weight | 262.25300 |
|---|
| Density | / | Boiling Point | / |
|---|
| Molecular Formula | C10H10D4N2O6 | Melting Point | / |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | 6-deuterio-1-[(2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trideuteriomethyl)pyrimidine-2,4-dione |
|---|
| Synonym | More Synonyms |
|---|
5-Methyluridine-d4 BiologicalActivity
| Description | 5-Methyluridine-d4 is the deuterium labeled 5-Methyluridine[1]. 5-Methyluridine is a is an endogenous methylated nucleoside found in human fluids[2]. |
|---|
| Related Catalog | Research Areas >>Others |
|---|
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
|---|
| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Yang TH, et al. Intracellular levels of S-adenosylhomocysteine but not homocysteine are highly correlated to the expression of nm23-H1 and the level of 5-methyldeoxycytidine in human hepatoma cells with different invasion activities. Nutr Cancer. 2006;55(2):224-31. |
|---|
Chemical & Physical Properties
| Molecular Formula | C10H10D4N2O6 |
|---|
| Molecular Weight | 262.25300 |
|---|
| Exact Mass | 262.11000 |
|---|
| PSA | 124.78000 |
|---|
| InChIKey | DWRXFEITVBNRMK-VZFAMDNFSA-N |
|---|
| SMILES | Cc1cn(C2OC(CO)C(O)C2O)c(=O)[nH]c1=O |
|---|
Synonyms
