CAS 7188-38-7|Tert-Butyl isocyanide

CHEMICAL IDENTIFICATION

RTECS NUMBER :

EQ7102500

CHEMICAL NAME :

tert-Butyl isocyanide

CAS REGISTRY NUMBER :

7188-38-7

LAST UPDATED :

199206

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C5-H9-N

MOLECULAR WEIGHT :

83.15

WISWESSER LINE NOTATION :

NCX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

710 mg/m3/4H

TOXIC EFFECTS :

Behavioral - changes in motor activity (specific assay)

REFERENCE :

ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 33,241,1975

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

377 mg/m3/4H

TOXIC EFFECTS :

Behavioral - changes in motor activity (specific assay)

REFERENCE :

ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 33,241,1975

J. Vis. Exp. (21) , doi:10.3791/942, (2008)

The optimization of a Ugi reaction involving the mixing of furfurylamine, benzaldehyde, boc-glycine and t-butylisocyanide is described. Triplicate runs of 48 parallel experiments are reported, varying...

J. Org. Chem. 77(22) , 10321-8, (2012)

A novel and highly efficient strategy for the synthesis of isocoumarins and phthalides through a palladium(0)-catalyzed reaction incorporating tert-butyl isocyanide has been developed. This process, p...

Org. Biomol. Chem. 8(16) , 3631-4, (2010)

With the development of a novel microwave-assisted one-pot tandem de-tert-butylation of tert-butyl amine in an Ugi-type multicomponent reaction product, tert-butyl isocyanide as a useful convertible i...