CAS 333-36-8|Fluorothyl
| Common Name | Fluorothyl | ||
|---|---|---|---|
| CAS Number | 333-36-8 | Molecular Weight | 182.06400 |
| Density | 1.404 g/mL at 25 °C(lit.) | Boiling Point | 62-63 °C(lit.) |
| Molecular Formula | C4H4F6O | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 35 °F |
| Symbol | GHS02, GHS07 | Signal Word | Danger |
Names
| Name | 1,1,1-trifluoro-2-(2,2,2-trifluoroethoxy)ethane |
|---|---|
| Synonym | More Synonyms |
Fluorothyl BiologicalActivity
| Description | Fluorothyl (Flurothyl) is a inhaling volatile liquid. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Others |
| References | [1]. Gao Y, et al. IL-33 Provides Neuroprotection through Suppressing Apoptotic, Autophagic and NF-κB-Mediated Inflammatory Pathways in a Rat Model of Recurrent Neonatal Seizure. Front Mol Neurosci. 2017 Dec 19;10:423. |
Chemical & Physical Properties
| Density | 1.404 g/mL at 25 °C(lit.) |
|---|---|
| Boiling Point | 62-63 °C(lit.) |
| Molecular Formula | C4H4F6O |
| Molecular Weight | 182.06400 |
| Flash Point | 35 °F |
| Exact Mass | 182.01700 |
| PSA | 9.23000 |
| LogP | 2.12760 |
| Index of Refraction | n20/D 1.300(lit.) |
| InChIKey | KGPPDNUWZNWPSI-UHFFFAOYSA-N |
| SMILES | FC(F)(F)COCC(F)(F)F |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1260 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 129,223,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 46 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 129,223,1960
Safety Information
| Symbol | GHS02, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H315-H319-H335 |
| Precautionary Statements | P210-P261-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US) |
| Hazard Codes | F,Xi,T |
| Risk Phrases | 11-36/37/38 |
| Safety Phrases | S16-S26-S36 |
| RIDADR | UN 3271 3/PG 2 |
| WGK Germany | 3 |
| RTECS | KN3675000 |
| Packaging Group | II |
| Hazard Class | 3.1 |
| HS Code | 2909199090 |
Customs
| HS Code | 2909199090 |
|---|---|
| Summary | 2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0% |
Articles39
More Articles| Spatiotemporal differences in the c-fos pathway between C57BL/6J and DBA/2J mice following flurothyl-induced seizures: A dissociation of hippocampal Fos from seizure activity. Epilepsy Res. 109 , 183-96, (2014) Significant differences in seizure characteristics between inbred mouse strains highlight the importance of genetic predisposition to epilepsy. Here, we examined the genetic differences between the se... | |
| Early life status epilepticus and stress have distinct and sex-specific effects on learning, subsequent seizure outcomes, including anticonvulsant response to phenobarbital. CNS Neurosci. Ther. 21(2) , 181-92, (2015) Neonatal status epilepticus (SE) is often associated with adverse cognitive and epilepsy outcomes. We investigate the effects of three episodes of kainic acid-induced SE (3KA-SE) and maternal separati... | |
| TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation. Neuron 79(6) , 1086-93, (2013) Dynamic changes in 5-methylcytosine (5mC) have been implicated in the regulation of gene expression critical for consolidation of memory. However, little is known about how these changes in 5mC are re... |
Synonyms
| Bis(2,2,2-trifluoroethyl)ether |
| 2,2,2-Trifluoroethyl Ether |
| Indoklon |
| Bis(2,2,2-trifluoroethyl) Ether |
| MFCD00010604 |
| 2,2,2-TRIFLUORO-N-(5-FLUOROTHIAZOL-2-YL)ACETAMIDE |
| HFE-356mf-f |
| Flurothyl |
| 2,2,2-trifluorodiethyl ether |
| Hexafluorodiethyl ether |
| Flurotyl |
| bis(trifluoroethyl) ether |
| Fluorothyl |
