Introduction：Basic information about CAS 699020-93-4|Immethridine 2HBr, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Immethridine 2HBr |
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| CAS Number | 699020-93-4 | Molecular Weight | 321.01200 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C9H11Br2N3 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 4-(1H-Imidazol-5-ylmethyl)pyridine dihydrobromide |
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Immethridine 2HBr BiologicalActivity
| Description | Immethridine dihydrobromide is a selective histamine H3 receptor (H3R) agonist. Immethridine dihydrobromide displays 300-fold selectivity over the H4 receptor and does not bind to H1 or H2 receptors. Immethridine dihydrobromide can be used for experimental autoimmune encephalomyelitis (EAE) research[1]. |
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| Related Catalog | Signaling Pathways >>Immunology/Inflammation >>Histamine ReceptorResearch Areas >>Inflammation/ImmunologySignaling Pathways >>GPCR/G Protein >>Histamine Receptor |
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| References | [1]. Shi Y, et al. Immethridine, histamine H3-receptor (H3R) agonist, alleviated experimental autoimmune encephalomyelitis via inhibiting the function of dendritic cells. Oncotarget. 2017 Aug 24;8(43):75038-75049. |
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Chemical & Physical Properties
| Molecular Formula | C9H11Br2N3 |
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| Molecular Weight | 321.01200 |
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| Exact Mass | 318.93200 |
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| PSA | 41.57000 |
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| LogP | 3.31170 |
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| InChIKey | CYNKWHIKNDIVDR-UHFFFAOYSA-N |
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| SMILES | Br.Br.c1cc(Cc2cnc[nH]2)ccn1 |
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