Introduction：Basic information about CAS 581065-95-4|Amino-PEG4-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Amino-PEG4-Boc |
|---|
| CAS Number | 581065-95-4 | Molecular Weight | 321.41000 |
|---|
| Density | 1.040±0.06 g/cm3 | Boiling Point | 400.1±35.0 ºC (760 Torr) |
|---|
| Molecular Formula | C15H31NO6 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 114.1±22.3 ºC |
|---|
Names
| Name | tert-butyl 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]propanoate |
|---|
| Synonym | More Synonyms |
|---|
Amino-PEG4-Boc BiologicalActivity
| Description | Amino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
|---|
| Target | PEGs Alkyl/ether |
|---|
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|
| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
|---|
Chemical & Physical Properties
| Density | 1.040±0.06 g/cm3 |
|---|
| Boiling Point | 400.1±35.0 ºC (760 Torr) |
|---|
| Molecular Formula | C15H31NO6 |
|---|
| Molecular Weight | 321.41000 |
|---|
| Flash Point | 114.1±22.3 ºC |
|---|
| Exact Mass | 321.21500 |
|---|
| PSA | 89.24000 |
|---|
| LogP | 1.44360 |
|---|
| Water Solubility | Freely soluble (140 g/L) (25 ºC) |
|---|
Synonyms
| 15-AMINO-4,7,10,13-TETRAOXA-PENTADECANOIC ACID T-BUTYL ESTER |
| 1-AMINO-3,6,9,12-BUTAOXAPENTADECAN-15-OIC ACID t-Butyl ester |
| tert-butyl 15-amino-4,7,10,13-tetraoxapentadecanoate |
| ter-butyl 1-amino-3,6,9,12-tetraoxapentadecan-15-oate |
| 15-Amino-4,7,10,13-tetraoxa-pentadecanoic-acid-tert-butylester |
| Amino-PEG4-t-butyl ester |
| AmbotzPEG1375 |
| 2-[2-[2-[2-(2-tert-Butoxycarbonylethoxy)ethoxy]ethoxy]ethoxy]ethylamine |
| H2N-PEG4-CH2CH2COOtBu |
