CAS 33620-72-3|Britannilactone

Introduction:Basic information about CAS 33620-72-3|Britannilactone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBritannilactone
CAS Number33620-72-3Molecular Weight266.33300
Density/Boiling Point/
Molecular FormulaC15H22O4Melting Point/
MSDS/Flash Point/

Names

Name4-hydroxy-6-(3-hydroxy-propyl)-5,7-dimethyl-3-methylene-3,3a,4,5,8,8a-hexahydro-cyclohepta[b]furan-2-one
SynonymMore Synonyms

Britannilactone BiologicalActivity

DescriptionBritannilactone(Desacetylinulicin) is a methanol extract of the dried flower of Inula britannica L.IC50 value:Target:A bioassay-guided isolation of the chloroform fraction of the I. britannica using an in vitro melanogenesis inhibition assay led to the isolation of sesquiterpenes, 1-O-acetylbritannilactone (1), britannilactone (2) and neobritannilactone B (3). Compounds 1 and 2 significantly reduced melanin production in a dose-dependent manner with IC50 values of 13.3 and 15.5 μM, respectively [1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>OthersNatural Products >>Terpenoids and Glycosides
References

[1]. Choo SJ, et al. Hypo-pigmenting effect of sesquiterpenes from Inula britannica in B16 melanoma cells. Arch Pharm Res. 2014 May;37(5):567-74.

Chemical & Physical Properties

Molecular FormulaC15H22O4
Molecular Weight266.33300
Exact Mass266.15200
PSA66.76000
LogP1.57390
InChIKeyASZIGQFYGXSPCO-UHFFFAOYSA-N
SMILESC=C1C(=O)OC2CC(C)=C(C(C)CCCO)C(O)C12
Storage condition2-8℃

Synonyms

Desacetylinulicin
BRITANNILACTONE
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