CAS 459-22-3|AM0210000 [RTECS]

Introduction：Basic information about CAS 459-22-3|AM0210000 [RTECS], including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles2
7. Synonyms

Common Name	AM0210000 [RTECS]
CAS Number	459-22-3	Molecular Weight	135.138
Density	1.1±0.1 g/cm3	Boiling Point	234.2±0.0 °C at 760 mmHg
Molecular Formula	C₈H₆FN	Melting Point	86ºC
MSDS	ChineseUSA	Flash Point	108.3±0.0 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	4-Fluorophenylacetonitrile
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	234.2±0.0 °C at 760 mmHg
Melting Point	86ºC
Molecular Formula	C₈H₆FN
Molecular Weight	135.138
Flash Point	108.3±0.0 °C
Exact Mass	135.048431
PSA	23.79000
LogP	1.50
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.508
InChIKey	JHQBLYITVCBGTO-UHFFFAOYSA-N
SMILES	N#CCc1ccc(F)cc1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AM0210000

CHEMICAL NAME :: Acetonitrile, (p-fluorophenyl)-

CAS REGISTRY NUMBER :: 459-22-3

BEILSTEIN REFERENCE NO. :: 1907764

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H6-F-N

MOLECULAR WEIGHT :: 135.15

WISWESSER LINE NOTATION :: NC1R DF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 42 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#07881

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302 + H312 + H332-H315-H319-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn:Harmful;
Risk Phrases	R20/21/22
Safety Phrases	S26-S36-S24/25-S26/36/37/39
RIDADR	UN 3276 6.1/PG 3
WGK Germany	3
RTECS	AM0210000
Packaging Group	III
Hazard Class	6.1
HS Code	2926909090

Customs

HS Code	2926909090
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles2

Biotransformation of phenylacetonitrile to 2-hydroxyphenylacetic acid by marine fungi.

Mar. Biotechnol. 15(1) , 97-103, (2013)

Marine fungi belonging to the genera Aspergillus, Penicillium, Cladosporium, and Bionectria catalyzed the biotransformation of phenylacetonitrile to 2-hydroxyphenylacetic acid. Eight marine fungi, sel...

Synthesis and pharmacological evaluation of 1-alkyl-N-[2-ethyl-2-(4-fluorophenyl)butyl]piperidine-4-carboxamide derivatives as novel antihypertensive agents.

Bioorg. Med. Chem. 19(18) , 5628-5638, (2011)

We synthesized and evaluated inhibitory activity against T-type Ca(2+) channels for a series of 1-alkyl-N-[2-ethyl-2-(4-fluorophenyl)butyl]piperidine-4-carboxamide derivatives. Structure-activity rela...

Synonyms

4-Fluorobenzeneacetonitrile

Benzeneacetonitrile, 4-fluoro-

4-Fluorobenzyl

4-Fluorophenylacetonitrile

Acetonitrile, (p-fluorophenyl)-

PARA-FLUOROBENZYL CYANIDE

p-Fluorobenzyl cyanide

2-(4-Fluorophenyl)acetonitrile

(p-Fluorophenyl)acetonitrile

4-FLUOROBENZYLNITRILE

MFCD00001917

p-Fluorobenzyl nitrile

4-Fluorobenzyl cyanide

4-Fluoroacetonitrile

(4-Fluorophenyl)acetonitrile

AM0210000 [RTECS]

EINECS 207-286-8

4-fluorobenzylacetonitrile

p-Fluorophenylacetonitrile

NC1R DF

Recommended......