Introduction：Basic information about CAS 62928-11-4|dichlorodihydroxybis(isopropylamine)platinum, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | dichlorodihydroxybis(isopropylamine)platinum |
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| CAS Number | 62928-11-4 | Molecular Weight | 418.21900 |
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| Density | / | Boiling Point | 30.9ºC at 760 mmHg |
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| Molecular Formula | C6H20Cl2N2O2Pt | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | dichlorodihydroxybis(isopropylamine)platinum |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Boiling Point | 30.9ºC at 760 mmHg |
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| Molecular Formula | C6H20Cl2N2O2Pt |
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| Molecular Weight | 418.21900 |
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| Exact Mass | 417.05500 |
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| PSA | 92.50000 |
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| LogP | 3.13050 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- TP2230500
- CHEMICAL NAME :
- Platinum(IV), bis(isopropylammine)-cis-dichloro-trans-dihydroxy-
- CAS REGISTRY NUMBER :
- 62928-11-4
- LAST UPDATED :
- 199803
- DATA ITEMS CITED :
- 16
- MOLECULAR FORMULA :
- C6-H20-Cl2-N2-O2-Pt
- MOLECULAR WEIGHT :
- 418.27
- WISWESSER LINE NOTATION :
- ZY1&1 2 &Q-PT-QGG
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 92 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 45 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 18 mg/kg/9W-I
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting Blood - leukopenia Blood - thrombocytopenia
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 17500 ug/kg/5D-I
- TOXIC EFFECTS :
- Gastrointestinal - alteration in gastric secretion Gastrointestinal - other changes
MUTATION DATA - TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- EJCODS European Journal of Cancer and Clinical Oncology. (Pergamon Press, c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.17(7)- 25, 1981-89. For publisher information, see EJCAEL Volume(issue)/page/year: 25,27,1989
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Synonyms
| Ab-dichloro-ce-dihydroxy-df-bis(isopropylamine)platinum |
| PLATINUM,DICHLORODIHYDROXYBIS(2-PROPANAMINE) |
| Iproplatin |
| [Pt(IV)Cl2(OH)2(NH2-i-Pr)2] |
| Platinum,dichlorodihydroxybis(2-propanamine)-,(oc-6-33) |
| EINECS 263-762-5 |
| cis,trans,cis-[Pt(isopropylamine)2(OH)2Cl2] |
| 2-Propanamine,platinum complex |
| cis-Dichloro-trans-dihydroxy-bis(isopropylamine)platinum |
| JM-9 |
| cis-dichloro-trans dihydroxy-cis-bis(isopropylamine)platinum(IV) |
| CHID |
